Pflügers Archiv

, Volume 379, Issue 1, pp 117–119 | Cite as

Evidence for an action of sodium ions in the activation of contraction of twitch muscle fibre

  • J. Caillé
  • M. Ildefonse
  • O. Rougier
Excitable Tissues and Central Nervous Physiology Letters and Notes


Simultaneous records in current clamp conditions of potential and of contraction of frog skeletal twitch muscle fibre have shown that a part of the contraction directly depends on the intervention of sodium ions (increase in presence of veratrine, decrease in lithium Ringer). The results confirm previous voltage clamp data and suggest a mechanism of sodium induced calcium release.

Key words

Frog twitch muscle Sodium ions Excitation contraction coupling 


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Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • J. Caillé
    • 1
  • M. Ildefonse
    • 1
  • O. Rougier
    • 1
  1. 1.Laboratoire de Physiologie des Eléments ExcitablesUniversité Claude BernardVilleurbanneFrance

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