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European Journal of Clinical Pharmacology

, Volume 29, Issue 6, pp 739–741 | Cite as

Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers

  • T. Leemann
  • P. Dayer
  • U. A. Meyer
Short Communications

Keywords

Oxidation Metoprolol Quinidine Extensive Metabolizers Quinidine Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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  8. Gut J, Gasser R, Dayer P, Kronbach T, Catin T, Meyer UA (1984) Debrisoquine-type polymorphism of drug oxidation: purification from human liver of a cytochrome P-450 isozyme with high activity for bufuralol hydroxylation. FEBS Lett 173: 287–290Google Scholar
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  16. Otton SV, Inaba T, Kalow W (1984) Competitive inhibition of sparteine oxidation in human liver by beta-adrenoceptor antagonists and other cardiovascular drugs. Life Sci 34: 73–80Google Scholar
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Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • T. Leemann
    • 1
  • P. Dayer
    • 1
  • U. A. Meyer
    • 2
  1. 1.Department of MedicineUniversity HospitalGenevaSwitzerland
  2. 2.Department of PharmacologyBiocenter of the UniversityBaselSwitzerland

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