European Archives of Oto-Rhino-Laryngology

, Volume 253, Issue 3, pp 142–146 | Cite as

Distribution of immunocompetent cells in various areas in the normal laryngeal mucosa of the rat

  • P. Jecker
  • M. Ptok
  • R. Pabst
  • J. Westermann
Original Paper

Abstract

The larynx can be divided into a supraglottic, a glottic and a subglottic area, each serving different functions. In many cases of laryngitis the site of infection is located in one area, leaving other areas unaffected. It seems reasonable to speculate that the underlying cause of the heterogeneous infection pattern in the larynx is the different processing of infectious agents. Therefore, the number and distribution of granulocytes, macrophages, dendritic cells, natural killer cells and T and B lymphocytes in the normal laryngeal mucosa of young rats were studied. The results show that, with the exception of granulocytes, all subpopulations were present in different numbers. Many macrophages and dendritic cells but only a few natural killer cells and T and B lymphocytes were located in the mucosa. Dendritic cells, natural killer cells and T and B lymphocytes were rarely present in the vocal fold area, whereas in the subglottic area they were present in high numbers. Thus, differences in the composition of immunocompetent cell populations between laryngeal areas were detectable.

Key words

Immunocompetent cells Mucosal immune system Larynx Immunohistology Rat 

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Copyright information

© Springer-Verlag 1996 1996

Authors and Affiliations

  • P. Jecker
    • 1
  • M. Ptok
    • 2
  • R. Pabst
    • 1
  • J. Westermann
    • 1
  1. 1.Zentrum Anatomic, Medizinische Hochschule HannoverHannoverGermany
  2. 2.Abteilung fur Phoniatrie and Pädaudiologie, Medizinische Hochschule HannoverHannoverGermany

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