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Spectral characteristics of visible radiation penetrating into the brain and stimulating extraretinal photoreceptors

Transmission recordings in vertebrates

Summary

Supravital recordings of spectral transmission in the brains of two species of teleosts (Anguilla anguilla, Ictalurus nebulosus), an amphibian (Rana temporaria), a reptile (Lacerta muralis), two species of birds (Passer domesticus, Columba livia), and a mammal (Phodopus sungorus) indicate that photons of longer wavelengths (700–750 nm) penetrate approximately 1,000 times more effectively into the hypothalamus than photons of shorter wavelengths (400–450 nm). The decrease in transmission from 750 to 400 nm is slightly interrupted by a plateau around 500 to 540 nm because of the transmission characteristics of hemoglobin. There is a small, ill-defined transmission minimum around 430 nm corresponding to the transmission minimum of melanin and hemoglobin (soret band). The high light sensitivity of deep diencephalic photoreceptors involved in the control of photoneuroendocrine events characteristic of some non-mammalian vertebrates suggests the occurrence of photopigment-containing receptors and nerve cells summating the input of several photoreceptors. However, in addition to photopigments, there may also exist other photosensitive compounds that mediate non-visual photoneuroendocrine responses.

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References

  • Benoit, J.: Etude de l'action des radiations visibles sur la gonadostimulation et de leur pénétration intracranienne chez les oiseaux et les mammifères. In: La photorégulation de la reproduction chez les oiseaux et les mammifères. Benoit, J., Assenmacher, I. (eds.), pp. 122–146, Paris: Centre Natl. Rech. Sci. 1970

    Google Scholar 

  • Comorosan, S., Sandru, D., Alexandrescu, E.: Oscillatory behaviour of enzymic reactions: a new phenomenon. Enzymologia38, 317–328 (1969)

    Google Scholar 

  • Deal, W.J., Erlanger, B.F., Nachmansohn, D.: Photoregulation of biological activity by photochromic reagents. III. Photoregulation of bioelectricity by acethylcholine receptor inhibitors. Proc. Natl. Acad. Sci. USA64, 1230–1234 (1969)

    Google Scholar 

  • Dodt, E.: Physical factors in the correlation of electroretinogram spectral sensitivity curves with visual pigments. Am. J. Ophthalmol.46, 87–91 (1958)

    Google Scholar 

  • Dodt, E.: The parietal eye (pineal and parietal organs) of lower vertebrates. In: Handbook of sensory physiology, Vol VII/3B. Jung, R. (ed.), pp. 113–140. Berlin, Heidelberg, New York: Springer 1973

    Google Scholar 

  • Farner, D.S. (ed.): Breeding biology of birds. Proceedings of a symposium on breeding-behavior and reproductive physiology in birds (Denver, 1972). Washington D.C.: Natl. Acad. Sci. USA 1973

    Google Scholar 

  • Frisch, K. von: Beiträge zur Physiologie der Pigmentzellen in der Fischhaut. Pflügers Arch.138, 319–387 (1911)

    Google Scholar 

  • Ganong, W.F., Shepherd, M.D., Wall, J.R., Brunt, E.E., Clegg, M.T. van: Penetration of light into the brain of mammals. Endocrinology72, 962–963 (1963)

    Google Scholar 

  • Hartwig, H.-G.: Neurobiologische Studien an photoneuroendokrinen Systemen, Habilitationsschrift, Fachbereich Humanmedizin, Justus-Liebig-Universität, Gießen (1975)

    Google Scholar 

  • Hogben, L.T., Slome, D.: The pigmentory effectory system. VI. The dual character of endocrine co-ordination in amphibian colour change. Proc. R. Soc. (Biol.)108, 10–53 (1931)

    Google Scholar 

  • Hollyfield, J.G., Witkovsky, P.: Pigment retinal epithelium involvement in photoreceptor development and function. J. Exp. Zool.189, 357–377 (1974)

    Google Scholar 

  • Hug, D.H., Roth, D., Hunter, J.K.: Photoactivation of an enzyme and biological photoreception: an hypothesis. Physiol. Phys.3, 353–360 (1971)

    Google Scholar 

  • McMillan, J.P., Underwood, H.A., Elliot, J.A., Stetson, M.H., Menaker, M.: Extraretinal light perception in the sparrow. 4. Further evidence that eyes do not participate in photoperiodic photoreception. J. comp. Physiol.97, 205–214 (1975)

    Google Scholar 

  • Menaker, M.: Rhythmus, reproduction, and photoreception. Biol. Reprod.4, 295–308 (1971a)

    Google Scholar 

  • Menaker, M.: Synchronization with the photic environment via extraretinal receptors. In: Biochronometry. Menaker, M. (ed.), pp. 315–322, Washington: Natl. Acad. Sci. USA 1971b

    Google Scholar 

  • Morita, Y.: Entladungsmuster pinealer Neurone der Regenbogenforelle (Salmo irideus) bei Belichtung des Zwischenhirns. Pflügers Arch.289, 155–167 (1966)

    Google Scholar 

  • Oksche, A., Hartwig, H.-G.: Photoneuroendocrine systems and the third ventricle. In: Brain-endocrine interaction. II. The ventricular system, 2nd Int. Symp., Shizuoka 1974. Knigge, K.M., et al. (eds.), pp. 40–53. Basel: Karger 1975

    Google Scholar 

  • Peregrin, J.: The influence of the intraocular blood content on the relative spectral sensitivity curves. Samml. Wiss. Arb. Med. Fak. Karls Univ. Hradi Král.17, 263–270 (1974)

    Google Scholar 

  • Sacerdote, M.: Differentiation of ectopic retinal structures in the hypothalamo-hypophysial area in the adult crested newt bearing a permanent hypothalamic lesion. Z. Anat. Entwicklungsgesch.134, 49–60 (1971)

    Google Scholar 

  • Schäfer, O.: Spektrale Empfindlichkeit und absolute Schwelle des Farbwechsels geblendeter Elritzen (Phoxinus phoxinus L.) Biol. Zentralbl.83, 47–66 (1964)

    Google Scholar 

  • Scharrer, E.: Die Lichtempfindlichkeit blinder Elritzen. (Untersuchungen über das Zwischenhirn der Fische). Z. vergl. Physiol.7, 1–38 (1928)

    Google Scholar 

  • Seliger, H.H., McElroy, W.D. (eds.): Light: Physical and biological action. New York, London: Academic Press 1965

    Google Scholar 

  • Veen, T. van, Hartwig, H.-G., Müller, K.: Light-dependent motor activity and photonegative behavior in the eel (Anguilla anguilla L.). Evidence for extraretinal and extrapineal photoreception. J. comp. Physiol.111, 209–219 (1976)

    Google Scholar 

  • Yokoyama, K., Oksche, A., Darden, Th.R., Farner, D.S.: The sites of encephalic photoreception in photoperiodic induction of the growth of the testes in the white-crowned sparrow,Zonotrichia leucophrys gambelii. Cell Tiss. Res.189, 441–467 (1978)

    Google Scholar 

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Supported by grants from the Deutsche Forschungsgemeinschaft to H.G.H. (Ha 726/4 and Ha 726/5). The authors are most grateful to Prof. D.S. Farner, Seattle, and Prof. E. Dodt, Bad Nauheim, for critically reading the manuscript, to Dr. R.L. Snipes, Giessen, for revision of the English text, to I. Lyncker and A. Löcherbach, Giessen, for skilful technical assistance

Supported by grants from the Swedish Natural Science Research Council (to P. Meurling and T. van Veen), and the Royal Physiographic Society of Lund

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Hartwig, H.G., van Veen, T. Spectral characteristics of visible radiation penetrating into the brain and stimulating extraretinal photoreceptors. J. Comp. Physiol. 130, 277–282 (1979). https://doi.org/10.1007/BF00614615

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Keywords

  • Radiation
  • Spectral Characteristic
  • Short Wavelength
  • Nerve Cell
  • Longe Wavelength