European Journal of Clinical Pharmacology

, Volume 32, Issue 1, pp 81–83 | Cite as

The effect of adrenaline in lignocaine anaesthetic solutions on plasma potassium in healthy volunteers

  • J. G. Meechan
  • M. D. Rawlins
Short Communications


Adrenaline, when administered in dental local anaesthetic solutions, significantly reduces the plasma potassium concentration in young healthy adults. This effect occurs within 10 min of extravascular injections into the maxillary buccal sulcus and may influence the choice of local anaesthetic solution for patients receiving kaliuretic diuretics.

Key words

adrenaline lignocaine dental local anaesthetic solutions potassium 


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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • J. G. Meechan
    • 1
  • M. D. Rawlins
    • 2
  1. 1.Department of Oral SurgeryThe University of Newcastle uponTyneEngland
  2. 2.The Wolfson Unit of Clinical PharmacologyThe University of Newcastle uponTyneEngland

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