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The effect of adrenaline in lignocaine anaesthetic solutions on plasma potassium in healthy volunteers

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Summary

Adrenaline, when administered in dental local anaesthetic solutions, significantly reduces the plasma potassium concentration in young healthy adults. This effect occurs within 10 min of extravascular injections into the maxillary buccal sulcus and may influence the choice of local anaesthetic solution for patients receiving kaliuretic diuretics.

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Authors and Affiliations

  1. Department of Oral Surgery, The University of Newcastle upon, Tyne, England

    J. G. Meechan

  2. The Wolfson Unit of Clinical Pharmacology, The University of Newcastle upon, Tyne, England

    M. D. Rawlins

Authors
  1. J. G. Meechan
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  2. M. D. Rawlins
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Meechan, J.G., Rawlins, M.D. The effect of adrenaline in lignocaine anaesthetic solutions on plasma potassium in healthy volunteers. Eur J Clin Pharmacol 32, 81–83 (1987). https://doi.org/10.1007/BF00609962

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  • DOI: https://doi.org/10.1007/BF00609962

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