European Radiology

, Volume 4, Issue 3, pp 268–270 | Cite as

Incidental discovery of a nonfunctioning islet-cell tumor 8 years after resection of an insulinoma: primary neoplasm or local recurrence?

  • Alexander A. Bankier
  • Michael N. Wiesmayr
  • Dominik Fleischmann
  • Gerhard H. Mostbeck
Case Reports Gastrointestinal Radiology


Two islet-cell tumors with uncommon radiological presentation were detected in a 48-year-old woman within a period of 8 years. Whereas the first tumor was an unusually large malignant insulinoma, the second (or recurrent) tumor was a non-functioning islet-cell tumor. Both tumors were studied~with with ultrasound and computed tomography.

Key words

Islet-cell tumor Endocrine activity Computed tomography 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Eckhauser FE, Cheung PS, Vinik AI, Stroder WE, Lloyd RV, Thompson NW (1986) Nonfunctioning malignant neuroendocrine tumors of the pancreas. Surgery 100: 978–987Google Scholar
  2. 2.
    Fugazzola C, Procacci C, Andreis JAB et al. (1990) The contribution of ultrasonography and computed tomography in the diagnosis of nonfunctioning islet-cell tumors of the pancreas. Gastrointest Radiol 15: 139–144Google Scholar
  3. 3.
    Eelkema EA, Stephens DH, Ward EM, Sheedy II PF (1984) CT features of nonfunctioning islet-cell carcinoma. AJR 143: 943–948Google Scholar
  4. 4.
    Paivansalo M, Makarainen H, Siniluoto T, Stahlberg M, Jalovaara P (1989) Ultrasound compared with computed tomography and pancreatic arteriography in the detection of endocrine tumors of the pancreas. Eur J Radiol 9: 173–178Google Scholar
  5. 5.
    Rossi P, Allison DJ, Bezzi M (1989) Endocrine tumors of the pancreas. Radiol Clin N Am 27: 129–161Google Scholar
  6. 6.
    Galiber AK, Reading CC, Charboneau JW et al. (1988) Localisation of pancreatic insulinoma: comparison of pre- and intraoperative US with CT and angiography. Radiology 166: 405–408Google Scholar
  7. 7.
    Pavone P, Mitchell DG, Leonetti F et al. (1993) Pancreatic betacell tumors: MRI. J Comput Assist Tomogr 17 (3): 403–407Google Scholar
  8. 8.
    Broughan TA, Leslie JD, Soto JM, Hermann RE (1986) Pancreatic islet-cell tumors. Surgery 99: 671–678Google Scholar
  9. 9.
    Ohneda A, Otsuki M, Fudjiya H, Yaginuma N, Kokubo T, Ohtani H (1979) A malignant insulinoma transformed into a glucagonoma syndrome. Diabetes 28: 962–969Google Scholar
  10. 10.
    Like AA, Orci L (1972) Embryogenesis of the human pancreatic islets: a light and electron microscopic study. Diabetes 21: 511–534Google Scholar
  11. 11.
    Schlossnagle DC, Campbell WG (1981) The papillary and solid neoplasm of the pancreas. Cancer 47: 2603–2610Google Scholar

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • Alexander A. Bankier
    • 1
  • Michael N. Wiesmayr
    • 1
  • Dominik Fleischmann
    • 1
  • Gerhard H. Mostbeck
    • 1
  1. 1.Department of Radiology, Ludwig Boltzmann Institute for Radiological and Physical Tumor DiagnosisUniversity of ViennaViennaAustria

Personalised recommendations