Mechanics of Composite Materials

, Volume 15, Issue 5, pp 580–584 | Cite as

Age-related changes in mechanical indices of compact bone tissue

  • M. A. Dobelis
Biocomposites
  • 34 Downloads

Conclusions

  1. 1.

    The mechanical indices of demineralized compact bone tissue upon tensile testing change with age. The greatest linear correlation was found for the initial modulus of elasticity E1 (r = 0.87). The mean tangential modulus of elasticity over the cross section doubles from age 24 to 52. The greatest linear correlation with age for strength indices is found for ultimate deformation ɛ11* (r = -0.94). Its mean value over the cross section decreases by a factor of 1.52.

     
  2. 2.

    The outer layer has higher mean strength indices and initial moduli of elasticity over the cross section, More regular and significant correlations with age are also found for the outer layer for all deformation and most strength indices. It is assumed that these differences in the age-related changes in the mechanical indices of the organic matrix over the thickness of the cortical layer of bone are mainly the result of structural nonuniformity.

     
  3. 3.

    The rate of change of the mechanical indices of demineralized compact bone tissue upon aging is nonuniform over the cross section. Biological aging has the greatest effect on the change in E1 and ɛ11* in zone 6 which, under normal physiological loads, functions primarily in tension.

     

Keywords

Tensile Testing Linear Correlation Bone Tissue Outer Layer Biological Aging 

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Literature cited

  1. 1.
    S. Chatterji and J. W. Jeffery, ″Changes in structure of human bone with age,″ Nature,219, 482–484 (1968).Google Scholar
  2. 2.
    J. W. T. Dickerson, ″Changes in the composition of the human femur during growth,″ Biochem. J.,82, 56–61 (1962).Google Scholar
  3. 3.
    H. Q. Woodard, ″The elementary composition of human cortical bone,″ Health Phys.,8, 513–517 (1962).Google Scholar
  4. 4.
    A. N. Polvakov, ″Age-related features of the mineral component of human bone tissue according to x-ray analysis and quantitative microroentgenography,″ Candidate's Dissertation of Medical Sciences, Moscow (1971).Google Scholar
  5. 5.
    D. M. Smith, H. R. A. Khairi, and C. C. Johnston, ″The loss of bone mineral with aging and its relationship to risk of fracture,″ J. Clin. Invest.,56, 311–318 (1975).Google Scholar
  6. 6.
    O. Lindahl and A. G. H. Lindgren, ″Cortical bone in man. 1. Variation of the amount and density with age and sex,″ Acta Orthop. Scand.,38, 133–140 (1967).Google Scholar
  7. 7.
    B. S. Mather, ″The effect of variation in specific gravity and ash content on the mechanical properties of human compact bone,″ J. Biomech.,1, 207–210 (1968).Google Scholar
  8. 8.
    Yu. Zh. Saulgozis, I. V. Knets, Kh. A. Yanson, and G. O. Pfafrod, ″Age-related changes of some elastic characteristics of the mechanical properties of human compact bone tissue,″ Mekh. Polim., No. 5, 885–891 (1974).Google Scholar
  9. 9.
    G. O. Pfafrod, L. I. Slutskii, A. F. Kregers, and Kh. A. Yanson, ″Age-related changes in the correlation between torsional strength and the biochemical coraposition of the human tibial bone,″ in: Biomechanics [in Russian], Riga (1975), pp. 32–43.Google Scholar
  10. 10.
    H. Vinz, ″Die Änderung der Materialeigenschaften und der stofflichen Zusammensetzung des kompakten Knochengewebes in Laufe der Altersentwicklung,″ Nova Acta Leopold.,35, 115 (1970).Google Scholar
  11. 11.
    F. G. Evans, Mechanical Properties of Bone, Illinois (1973).Google Scholar
  12. 12.
    R. D. Harkness, ″Biological function of collagen,″ Biol. Rev.,36, 399–463 (1961).Google Scholar
  13. 13.
    M. D. Ridge and V. Wright, ″The rheology of skin: a bioengineering study of the mechanical properties of human skin in relation to its structure,″ Brit. J. Dermatol.,77, 639–649 (1965).Google Scholar
  14. 14.
    H. R. Elden, ″Physical properties of collagen fibers,″ in: Int. Rev. Connective Tissue Res., Vol. 4, 283–348 (1968).Google Scholar
  15. 15.
    A. Viidik, Function and Structure of Collagenous Tissue, Elanders Boktryckeri Aktiebolag, Göteborg (1968).Google Scholar
  16. 16.
    J. Diamant, A. Keller, E. Baer, M. Litt, and R. Arridge, ″Collagen: ultrastructure and its relation to mechanical properties as a function of aging,″ Proc. Ry. Soc.,B180, 293–315 (1972).Google Scholar
  17. 17.
    E. Baer, A. Hiltner, and B. Friedman, ″Correlations between the ultrastructure and mechanical properties in tendon collagen, a highly-ordered macromolecular composite,″ Mekh. Polim., No. 6, 1051–1060 (1975).Google Scholar
  18. 18.
    H. Rollhäuser, ″Konstitutions- und Alteruntershiede in Festigkeit Kollagener Fibrillen,″ Gegenbaurs, Morph. Jb.,90, 157–179 (1950).Google Scholar
  19. 19.
    M. A. Dobelis, ″Deformation properties of demineralized human compact bone tissue in tensile testing,″ Mekh. Polim., No. 1, 101–108 (1978).Google Scholar
  20. 20.
    M. A. Dobelis, ″The strength properties of demineralized human compact bone tissue,″ Abstr. Conf. Young Specialists on Polymer Mechanics [in Russian], Riga (1977), pp. 63–65.Google Scholar
  21. 21.
    T. Kimura, ″Mechanical characteristics of human lower leg bones,″ J. Fac. Sci., Univ. Tokyo, Sect. 5,4, 319–393 (1974).Google Scholar

Copyright information

© Plenum Publishing Corporation 1980

Authors and Affiliations

  • M. A. Dobelis
    • 1
  1. 1.Institute of Polymer MechanicsAcademy of Sciences of the Latvian SSRRiga

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