Abstract
A comparative study has been made of methods of synthesizing substituted β-phenylethylamines via the corresponding nitriles and via nitrostyrenes, and a superiority of the latter method has been established. The possibility has been shown for the first time of reducing nitrostyrenes to saturated amines with diisobutylaluminum hydride (DIBAH). The use of DIBAH as reducing agent enables amines to be obtained in high yields.
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Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Chemistry, Bashkir Scientific Center, Urals Branch, Academy of Sciences of the USSR, Ufa. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 67–74, January–February, 1990.
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Vinogradova, V.I., Yunusov, M.S., Kuchin, A.V. et al. Syntheses based onβ-phenylethylamines. I. Preparation of substitutedβ-phenylethylamines. Chem Nat Compd 26, 54–59 (1990). https://doi.org/10.1007/BF00605201
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DOI: https://doi.org/10.1007/BF00605201