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Archiv für dermatologische Forschung

, Volume 241, Issue 1, pp 15–21 | Cite as

Immunofluorescent studies on circulating lymphocytes in oral mucosal diseases

  • K. Sallay
  • P. Dán
  • P. Geck
  • G. Kulcsár
  • I. Nász
Article

Summary

Circulating lymphocytes of patients with recurrent herpetic, aphthous and other oral mucosal diseases, as well as of persons with intact oral mucosa were examined with direct immunofluorescence method using HVH and adenovirus hyperimmune conjugated sera. Some of the circulating lymphocytes showed a specific fluorescence both in patients and in persons with intact oral mucosa. Increased herpes-positivity was observed only in erythema exsudativum multiforme and increased adeno-positivity in patients with recurrent aphthous stomatitis, especially in cases with constantly recurring aphthae.

The possible pathologic role of the circulating virus-antigen-carrier lymphocytes is presumed.

Keywords

Public Health Oral Mucosa Stomatitis Immunofluorescent Study Erythema Multiforme 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Es wurden Untersuchungen mit der direkten Immunfluorescenzmethode bei Kranken mit rezidivierenden herpetischen, aphthösen und anderen Mundschleimhautkrankheiten mit Antiherpes- und Antiadenoviruskonjugaten durchgeführt. Sowohl bei den Patienten wie bei den Personen mit intakter Mundschleimhaut wurde eine spezifische Fluorescenz beobachtet. Erhöhte Adenopositivität wurde bei Patienten mit rezidivierenden, besonders mit ständig rezidivierenden Aphthen, erhöhte Herpespositivität bei Kranken mit Erythema multiforme beobachtet.

Die mögliche pathologische Rolle der virusantigen-haltenden Lymphocyten wurde angenommen.

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Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • K. Sallay
    • 1
    • 2
  • P. Dán
    • 1
    • 2
  • P. Geck
    • 1
    • 2
  • G. Kulcsár
    • 1
    • 2
  • I. Nász
    • 1
    • 2
  1. 1.Institute of Oral and Maxillo-facial SurgerySemmelweis University of MedicineBudapestHungary
  2. 2.Institute of MicrobiologySemmelweis University of MedicineBudapestHungary

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