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Journal of Comparative Physiology A

, Volume 163, Issue 3, pp 339–348 | Cite as

Influence of photoperiod and gonadal steroids on hibernation in the European hamster

  • Janet M. Darrow
  • Marilyn J. Duncan
  • Andrzej Bartke
  • Antonella Bona-Gallo
  • Bruce D. Goldman
Article

Summary

Torpor was monitored daily in adult male and female European hamsters (Cricetus cricetus) induced to hibernate by exposure to a cold environment (6 °C). The effect of photoperiodic manipulations or administration of exogenous gonadal steroids was examined in gonadectomized or intact hamsters.
  1. 1.

    Gonadal regression occurred in all short day, but only in some long day, cold-exposed hamsters. Entry into hibernation was not observed until reproductive regression had occurred. Thus, gonadal atrophy appears to be a necessary precondition for hibernation.

     
  2. 2.

    Castrated hamsters in the short day cold condition showed a significantly greater incidence of torpor than those in the long day cold condition. Hence, photoperiod affected torpor independently of its effect on the gonadal cycle.

     
  3. 3.

    Testosterone, when administered via silastic capsules at near physiological levels, completely inhibited torpor in gonadectomized male and female hamsters hibernating in the short day cold condition.

     
  4. 4.

    In ovariectomized females, torpor was unaffected by progesterone treatment, but partially inhibited by estradiol. A greater inhibition of torpor was observed when estradiol-primed females were administered both estradiol and progesterone simultaneously. Thus, the effect of both hormones may be functionally comparable to that of the single testicular hormone.

     
  5. 5.

    Estradiol inhibited torpor to a greater extent in intact and ovariectomized female hamsters hibernating in long days than those in short days, suggesting an effect of photoperiod on responsiveness to estradiol.

     

These results indicate an inverse relationship between the gonadal and hibernation cycles, and a probable role for gonadal steroids to influence the timing of the hibernation season. However, non-gonadal factors must also be involved in controlling hibernation, since photoperiod affected the incidence of torpor in gonadectomized animals and because hamsters were able to terminate hibernation in the absence of gonadal hormones.

Keywords

Estradiol Cold Condition Gonadal Steroid Gonadal Hormone Progesterone Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Barnes BM (1986) Annual cycles of gonadotropins and androgens in the hibernating golden-mantled ground squirrel. Gen Comp Endocrinol 62:13–22Google Scholar
  2. Bartke A, Steele RE, Musto N, Caldwell BV (1973) Fluctuations in plasma testosterone levels in adult male rats and mice. Endocrinology 92:1223–1228Google Scholar
  3. Blizard DA (1983) Sex differences in running-wheel behaviour in the rat: The inductive and activational effects of gonadal hormones. Anim Behav 31:378–384Google Scholar
  4. Buijs RM, Pevet P, Masson-Pevet M, Pool CW, deVries GJ, Canguilhem B, Vivien-Roels B (1986) Seasonal variation in vasopressin innervation in the brain of the European hamster (Cricetus cricetus) Brain Res 371:193–196Google Scholar
  5. Canguilhem B, Miro JL, Kemp E, Schmitt P (1986) Does serotonin play a role in entrance into hibernation? Am J Physiol 251:R755–761Google Scholar
  6. Darrow JM, Tamarkin L, Duncan MJ, Goldman BD (1986) Pineal melatonin rhythms in female Turkish hamsters: effects of photoperiod and hibernation. Biol Reprod 35:74–83Google Scholar
  7. Darrow JM, Yogev L, Goldman BD (1987) Patterns of reproductive hormone secretion in hibernating Turkish hamsters. Am J Physiol 253: R329-R336Google Scholar
  8. Elliott JA, Bartness TJ, Goldman BD (1987) Role of short photoperiod and cold exposure in regulating daily torpor in Djungarian hamsters. J Comp Physiol A 161:245–253Google Scholar
  9. Ellis GB, Turek FH (1979) Time course of the photoperiod-induced change in sensitivity of the hypothalamic-pituitary axis to testosterone feedback in castrated male hamsters. Endocrinology 104:625–630Google Scholar
  10. Gentry RT, Wade GN (1976) Sex differences in sensitivity of food intake, body weight and running-wheel activity to ovarian steroids in rats. J Comp Physiol Psychol 90:747–754Google Scholar
  11. Goldman BD (1980) Seasonal cycles in testis function in two hamster species: relation to photoperiod and hibernation. In: Steinberger A, Steinberger E (eds) Testicular development, structure and function. Raven Press, New York, pp 401–409Google Scholar
  12. Goldman BD, Darrow JM (1987) Effects of photoperiod on hibernation in castrated Turkish hamsters. Am J Physiol 253:R337-R343Google Scholar
  13. Hall VD (1981) Seasonal cycles in gonadal function and hibernation in the Turkish hamster (Mesocricetus brandti). PhD dissertation, University of ConnecticutGoogle Scholar
  14. Hall VD, Goldman BD (1980) Effects of gonadal steroid hormones on hibernation in the Turkish hamster (Mesocricetus brandti). J Comp Physiol 135:107–114Google Scholar
  15. Hall VD, Goldman BD (1982) Hibernation in the female Turkish hamster (Mesocricetus brandti): an investigation of the role of the ovaries and of photoperiod. Biol Reprod 27:811–815Google Scholar
  16. Hall VD, Bartke A, Goldman BD (1982) Role of the testis in regulating the duration of hibernation in the Turkish hamster,Mesocricetus brandti. Biol Reprod 27:802–810Google Scholar
  17. Heller HC (1979) Hibernation: neural aspects. Annu Rev Physiol 41:305–321Google Scholar
  18. Jallageas M, Assenmacher I (1983) Annual plasma testosterone and thyroxine cycles in relation to hibernation in the edible dormouseGlis glis. Gen Comp Endocrinol 50:452–462Google Scholar
  19. Jansky L, Hadded G, Kahlerova Z, Nedoma J (1984) Effect of external factors on hibernation of golden hamsters. J Comp Physiol B 154:427–433Google Scholar
  20. Leipheimer RE, Bona-Gallo A, Gallo RV (1984) The influence of progesterone and estradiol on the acute changes in pulsatile LH release induced by ovariectomy on diestrus day 1 in the rat. Endocrinology 114:1605–1612Google Scholar
  21. Lyman CP, Chatfield PO (1955) Physiology of hibernation in mammals. Physiol Rev 35:403–425Google Scholar
  22. Malan A (1969) Controle hypothalamique de la thermoregulation et de l'hibernation chez le hamster d'EuropeCricetus cricetus. Arch Sci Physiol 23:47–87Google Scholar
  23. Okulicz WC (1986) Progesterone receptor replenishment during sustained progesterone treatment in the hamster uterus. Endocrinology 118:2488–2494Google Scholar
  24. Okulicz WC, Darrow JM, Goldman BD (1988) Uterine steroid hormone receptors during the estrous cycle and during hibernation in the Turkish hamster (Mesocricetus brandti). Biol Reprod 38:597–604Google Scholar
  25. Raths P, Bohn A (1975) Der Einfluß von Hirnstammläsionen auf den Winterschlaf des Hamsters (Cricetus cricetus L.). Acta Biol Med Germ 34:1189–1198Google Scholar
  26. Reznik-Schuller H, Reznik G (1973) Comparative histometric investigations of the testicular function of European hamsters (Cricetus cricetus) with and without hibernation. Fertil Steril 24:698–705Google Scholar
  27. Scott I, D'Agostino G, Cernova T, Becker L, Giovinazzo L (1981) Seasonal testosterone in the Eastern Chipmunk,Tamias striatus. Cryobiology 18:89Google Scholar
  28. Smit-Vis JH (1972) The effect of pinealectomy and of testosterone administration on the occurrence of hibernation in adult male golden hamsters. Acta Morphol Neerl-Scand 10:269–281Google Scholar
  29. Vitale PM, Darrow JM, Duncan MJ, Shustak CA, Goldman BD (1985) Effects of photoperiod, pinealectomy and castration on body weight and daily torpor in Djungarian hamsters (Phodopus sungorus). J Endocrinol 106:367–375Google Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • Janet M. Darrow
    • 1
  • Marilyn J. Duncan
    • 1
  • Andrzej Bartke
    • 1
    • 2
  • Antonella Bona-Gallo
    • 1
    • 3
  • Bruce D. Goldman
    • 1
  1. 1.Worcester Foundation for Experimental BiologyShrewsburyUSA
  2. 2.Department of PhysiologySouthern Illinois University School of MedicineCarbondaleUSA
  3. 3.Department of Physiology and NeurobiologyUniversity of ConnecticutStorrsUSA

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