Pflügers Archiv

, Volume 332, Issue 1, pp 10–20 | Cite as

Effects of lenticular stimulation on unitary and mass responses of the visual cortex to light

  • Iwao Kadobayashi


Effects of lenticular stimulation on unitary and mass responses of the visual cortex were studied in acutely prepared cats. A conditioning shock applied to the lenticular nucleus (globus pallidus and putamen) resulted in an increase in amplitude of primary components of the photically evoked potential in the lateral gyrus. The increase in amplitude of the evoked potential was observed not only in the ipsilateral visual cortex but also in the contralateral one. Marked increase was noted at several conditioning-test intervals. Unitary responses of visual cortical cells to light were enhanced or inhibited by the conditioning shock to the lenticular nucleus. In units which fired primarily after flash, enhancement of firing was observed more commonly than inhibition, but in units which showed a primary neuronal silence after light, it was vice versa. It is concluded that the lenticular nucleus participates in the visual cortical activity.

Key words

Globus Pallidus Putamen Photic Response Visual Cortex 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Battersby, W. S., Oesterreich, R. E.: Neural limitations of visual excitability. VI. Photic enhancement following lateral thalamic stimulation. Electroenceph. clin. Neurophysiol.15, 849–865 (1963).Google Scholar
  2. 2.
    Baumgartner, G.: Reaktionen einzelner Neurone im optischen Cortex der Katze nach Lichtblitzen. Pflügers Arch. ges. Physiol.261, 457–469 (1955).Google Scholar
  3. 3.
    Bremer, F., Stoupel, N.: De la modification des réponses sensorielles corticales dans l'éveil réticulaire. Acta neurol. belg.58, 401–403 (1958).Google Scholar
  4. 4.
    Brown, T. S., Marco, L. A.: Effects of stimulation of the superior colliculus and lateral thalamus on visual evoked potentials. Electroenceph. clin. Neurophysiol.22, 150–158 (1967).Google Scholar
  5. 5.
    Buchwald, N. A., Rakic, L., Wyers, E. J., Hull, C., Heuser, G.: Integration of visual impulses and the “caudate loop”. Exp. Neurol.5, 1–20 (1962).Google Scholar
  6. 6.
    Creutzfeldt, O. D., Akimoto, H.: Konvergenz und gegenseitige Beeinflussung von Impulsen aus der Retina und den unspezifischen Thalamuskernen an einzelnen Neuronen des optischen Cortex. Arch. Psychiat. Nervenkr.196, 520–538 (1958).Google Scholar
  7. 7.
    —, Rosina, A., Ito, M., Probst, W.: Visual evoked response of single cells and of the EEG in primary visual area of the cat. J. Neurophysiol.32, 127–139 (1969).Google Scholar
  8. 8.
    Demetrescu, M., Demetrescu, Maria: The inhibitory action of the caudate nucleus in cortical primary receiving areas in the cat. Electroenceph. clin. Neurophysiol.14, 37–52 (1962).Google Scholar
  9. 9.
    Dumont, S., Dell, P.: Facilitations spécifiques et nonspécifiques des réponses visuelles corticales. J. Physiol. (Paris)50, 261–264 (1958).Google Scholar
  10. 10.
    Fox, S. S., O'Brien, J. H.: Inhibition and facilitation of afferent information by the caudate nucleus. Science137, 423–425 (1962).Google Scholar
  11. 10.
    —: Duplication of evoked potential waveform by curve of probability of firing of a single cell. Science147, 888–890 (1965).Google Scholar
  12. 12.
    Fromm, G. H., Bond, H. W.: The relationship between neuron activity and cortical steady potentials. Electroenceph. clin. Neurophysiol.22, 159–166 (1967).Google Scholar
  13. 13.
    Frost, J. D.: EEG-intracellular potential relationships in isolated cerebral cortex. Electroenceph. clin. Neurophysiol.24, 434–443 (1968).Google Scholar
  14. 14.
    Fuster, J. M.: Excitation and inhibition of neuronal firing in visual cortex by reticular stimulation. Science133, 2011–2012 (1961).Google Scholar
  15. 15.
    —, Creutzfeldt, O. D., Straschill, M.: Intracellular recording of neuronal activity in the visual system. Z. vergl. Physiol.49, 605–622 (1965).Google Scholar
  16. 16.
    Jasper, H. H., Ajmone-Marsan, C.: A stereotaxic atlas of the diencephalon of the cat. Ottawa: National Research Council of Canada 1954.Google Scholar
  17. 17.
    Johnson, T. N., Clemente, C. D.: An experimental study of the fiber connections between the putamen, globus pallidus, ventral thalamus and midbrain tegmentum in cat. J. comp. Neurol.113, 83–101 (1959).Google Scholar
  18. 18.
    Jung, R., Baumgarten, R. V., Baumgartner, G.: Mikroableitungen von einzelnen Nervenzellen im optischen Cortex der Katze: Die lichtaktivierten B-Neurone. Arch. Psychiat. Nervenkr.189, 521–539 (1952).Google Scholar
  19. 19.
    —, Hassler, R.: The extrapyramidal motor system. In: Handbook of Physiology. Neurophysiology, vol. II, pp. 863–927. Washington: American Physiological Society 1960.Google Scholar
  20. 20.
    Kadobayashi, I., Ukida, G.: Effects of lenticular stimulation on unitary responses of the lateral geniculate body to light. Exp. Neurol. (in press).Google Scholar
  21. 21.
    Krauthamer, G., Albe-Fessard, D.: Inhibition of nonspecific sensory activities following striopallidal and capsular stimulation. J. Neurophysiol.28, 100–124 (1965).Google Scholar
  22. 22.
    Lehmann, D., Koukkou, M.: Neuronal Effekte der Caudatumreizung im visuellen Cortex. Pflügers Arch. ges. Physiol.280, 297–315 (1964).Google Scholar
  23. 23.
    Li, C.-L., Cullen, C., Jasper, H. H.: Laminar microelectrode studies of specific somatosensory cortical potentials. J. Neurophysiol.19, 111–130 (1956).Google Scholar
  24. 24.
    McIlwain, J. T., Creutzfeldt, O. D.: Microelectrode study of synaptic excitation and inhibition in the lateral geniculate nucleus of the cat. J. Neurophysiol.30, 1–21 (1967).Google Scholar
  25. 25.
    Nauta, W. J. H., Mehler, W. R.: Some efferent connections of the lentiform nucleus in monkey and cat. Anat. Rec.139, 260 (1961).Google Scholar
  26. 26.
    Poggio, G. F., Baker, F. H., Lamarre, Y., Riva Sanseverino, E.: Afferent inhibition at input to visual cortex of the cat. J. Neurophysiol.32, 892–915 (1969).Google Scholar
  27. 27.
    Purpura, D. P., Shofer, R. J., Musgrave, F. S.: Cortical intracellular potentials during augmenting and recruiting responses. II. Patterns of synaptic activities in pyramidal and nonpyramidal tract neurons. J. Neurophysiol.27, 133–151 (1964).Google Scholar
  28. 28.
    Ranson, S. W., Ranson, S. W., Jr., Ranson, M.: Fiber connections of corpus striatum as seen in Marchi preparations. Arch. Neurol. Psychiat. (Chic.)46, 230–249 (1941).Google Scholar
  29. 29.
    Rose, G. H., Lindsley, D. B.: Development of visually evoked potentials in kittens: specific and nonspecific responses. J. Neurophysiol.31, 607–623 (1968).Google Scholar
  30. 30.
    Satinsky, D.: Reticular influences on lateral geniculate neuron activity. Electroenceph. clin. Neurophysiol.25, 543–549 (1968).Google Scholar
  31. 31.
    Szabo, J.: Topical distribution of striatal efferents in the monkey. Exp. Neurol.5, 21–36 (1962).Google Scholar
  32. 32.
    Verzeano, M., Dill, R. C., Vallecalle, E., Groves, P., Thomas, J.: Evoked responses and neuronal activity in the lateral geniculate. Experientia (Basel)24, 696–698 (1968).Google Scholar

Copyright information

© Springer-Verlag 1972

Authors and Affiliations

  • Iwao Kadobayashi
    • 1
  1. 1.Department of PsychiatryKyoto Prefectural University of MedicineKyotoJapan

Personalised recommendations