Dynamic enhancement MRI of anterior lobe in pituitary dwarfism
- 55 Downloads
We examined 23 patients with pituitary dwarfism by dynamic MRI; with a repetition time of 150 or 50 ms. The time-enhancement difference curves of selected regions in the anterior lobes were plotted. Another 48 patients with no definite clinical pituitary disfunction were examined with the same technique. We found that the intensity of maximum enhancement in both groups was similar, but the time to achieve maximum enhancement was delayed in pituitary dwarfism with or without stalk transection; the time seemed longest with stalk transection. There was little difference in enhancement between patients with multiple hormone deficiency or isolated growth hormone deficiency. Dynamic MRI of the anterior lobes may be an important functional imaging study, and our results imply that poor perfusion is a useful finding in pituitary dwarfism, especially in patients without stalk transection and normal pituitary height.
Key wordsDynamic contrast enhancement Pituitary dwarfism Magnetic resonance imaging
Unable to display preview. Download preview PDF.
- 1.Kelly WM, Kucharczyk W, Kucharczyk J, Kjos B, Peck WW, Norman D, Newton TH (1988) Posterior pituitary ectopia: an MR feature of pituitary dwarfism. AJNR 9:453–460Google Scholar
- 2.Abrahams JJ, Trefelner E, Boulware SD (1991) Idiopathic growth hormone deficiency: MR findings in 35 patients. AJNR 12:155–160Google Scholar
- 3.Kuroiwa T, Okabe Y, Hasuo K, Yasumori K, Mizushima A, Masuda K (1991) MR imaging of pituitary dwarfism. AJNR 12:161–164Google Scholar
- 4.Cacciari W, Zucchini S, Carla G, Pirrazzoli P, Cicognani A, Mandini M, Busacca M, Trevisan C (1990) Endocrine function and morphological findings in patients with disorders of the hypothalamo-pituitary area: a study with magnetic resonance. Arch Dis Child 65:1199–1202Google Scholar
- 5.Miki Y, Matsuo M, Nishizawa S, Kuroda Y, Kevaki A, Makita Y, Kawamura J (1990) Pituitary adenomas and normal pituitary tissue: enhancement patterns on gadopentetate-enhanced MR imaging. Radiology 177:35–38Google Scholar
- 6.Sakamoto Y, Takahashi M, Korogi Y, Bussaka H, Ushio Y (1991) Normal and abnormal pituitary glands: gadopentetate dimeglumine-enhanced MR imaging. Radiology 178:441–445Google Scholar
- 7.Tien RD (1992) Sequence of enhancement of various portions of the pituitary gland on gadolinium-enhanced MR imaging: correlation with regional blood supply. AJR 158:651–654Google Scholar
- 8.Inoue Y, Nemoto, Fujita K, Aoki H, Takemoto K, Tsukamoto Y, Oda J, Onoyama Y (1986) Pituitary dwarfism: CT evaluation of the pituitary gland. Radiology 159:171–173Google Scholar
- 9.Baker BL (1974) Functional cytology of the hypophysial pars distalis and pars intermediate. In: Greep RO, Astwood EB, Knobil E, Sawyer, WH, Geiger SR (eds) Handbook of physiology, section 7. Endocrinology, vol IV, part 1. The pituitary gland and its neuroendocrine control. American Physiological Society, Washington DC, pp 45–80Google Scholar