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Chemistry of Natural Compounds

, Volume 22, Issue 5, pp 560–565 | Cite as

Withasteroids ofPhysalis. VII. 14α-Hydroxyixocarpanolide and 24,25-expoxywithanolide D

  • O. E. Vasina
  • V. A. Maslennikova
  • N. D. Abdullaev
  • N. K. Abubakirov
Article

Abstract

Two new withasteroid have been isolated fromPhysalis angulata L. — 14α-hydroxyixocarpanolide and 24,25-epoxywithanolide D. 14α-hydroxyixocarpanolide — C28H40O7, mp 245–250°C (from methanol), [α] D 20 +29±2° (chloroform). 24,25-Epoxywithanolide D — C28H38O7, mp 257–261°C (from methanol, [α] D 20 +23±2° (chloroform). On the basis of its UV, IR, CD, mass, and1H and13C NMR spectra the structure of 5α,14α,20R-trihydroxy-1-oxo-6α,7α-epoxy-22R-2itha-2-enolide is suggested for 14α-hydroxyixocarpanolide. On the basis of spectral characteristics and the preparation of 4β-acetoxy and 4-oxo derivatives of 24,25-epoxywithanolide D, the structure of 4β,20R-dihydroxy-1-oxo-5β,6β;24S,25S-diepoxy-22R-witha-2-enolide is proposed for it.

Keywords

Hydroxy Group Lactone Grouping Lactone Moiety Steroid Moiety Membered Lactone Ring 

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Copyright information

© Plenum Publishing Corporation 1987

Authors and Affiliations

  • O. E. Vasina
  • V. A. Maslennikova
  • N. D. Abdullaev
  • N. K. Abubakirov

There are no affiliations available

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