Magnetic resonance imaging and histopathology of cerebral gliomas

Neuroradiology volume 34, pages463–469(1992)Cite this article

Summary

The correlation of magnetic resonance imaging (MRI) with histopathological findings was analysed in 26 patients with untreated cerebral gliomas. In low-grade gliomas, T2-weighted images demonstrated relatively homogeneous high-intensity lesions involving both the grey and the white matter. In high-grade gliomas, especially grade IV, T2-weighted images demonstrated prominent heterogeneity in signal intensity, which consisted of a hyperintense “core”, less hyperintense or normal intensity “rim” and surrounding finger-like areas of high intensity. Marked and irregular contrast enhancement was evident in all but one case of these high-grade gliomas in which gadolinium-DTPA was used. Histological examination revealed tumour cells extending as far as the borders of the high-intensity areas shown on T2-weighted images in both high-and low-grade gliomas, but in 5 of 8 low-grade and 4 of 18 high-grade gliomas, isolated tumour cells extended beyond the hyperintense areas shown on T2-weighted images.

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Affiliations

  1. Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan

    M. Watanabe, R. Tanaka & N. Takeda

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  1. M. Watanabe
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  2. R. Tanaka
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  3. N. Takeda
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Watanabe, M., Tanaka, R. & Takeda, N. Magnetic resonance imaging and histopathology of cerebral gliomas. Neuroradiology 34, 463–469 (1992). https://doi.org/10.1007/BF00598951

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Key words

  • Cerebral glioma
  • Histopathology
  • Magnetic resonance imaging
  • Gadolinium-DTPA