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Modification of DNA by photoactivable aryl azides

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Abstract

Features of the interaction with DNA of photoactivable aryl azides having various substituents in the aromatic ring have been studied. The nature of the interaction with DNA and the degree of its modification depend substantially on the nature of these substituents. The results obtained can be used for obtaining DNA probes bearing various marker groups.

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Authors
  1. N. N. Veiko
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  2. A. V. Karpukhin
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  3. A. G. Salimov
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  4. D. N. Spitkovskii
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Additional information

Institute of Medical Genetics, Academy of Medical Sciences of USSR, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 259–263, March–April, 1989.

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Veiko, N.N., Karpukhin, A.V., Salimov, A.G. et al. Modification of DNA by photoactivable aryl azides. Chem Nat Compd 25, 224–228 (1989). https://doi.org/10.1007/BF00598417

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  • DOI: https://doi.org/10.1007/BF00598417

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