Chemistry of Natural Compounds

, Volume 26, Issue 3, pp 271–274 | Cite as

Isolation of preparations with a high content of eicosapentaenoic acid from the red marine alga Palmaria stenogona

  • N. A. Romashina
  • V. E. Vas'kovskii


The composition is given of the fatty acids of the red marine algaPalmaria stenogona. The amount of eicosapentaenoic acid (EPA) in the alga was 69.9–77.0% of the total fatty acids. The procedure for isolating EPA of 80–90% purity from the alga is described which includes the saponification of the algal lipids, the selective extraction of the unsaponifiable lipids, the isolation of the free fatty acids, and their separation by the method of crystallizing inclusion complexes of the fatty acids with urea.


Eicosapentaenoic Acid Silver Nitrate Caustic Soda Enoic Acid Polyenoic Fatty Acid 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    J. Tinoco, Prog. Lipid Res.,21, 1 (1982).CrossRefGoogle Scholar
  2. 2.
    T. Watanabe, Comp. Biochem. Physiol.,73B, No. 1, 3 (1982).Google Scholar
  3. 3.
    C. B. Block, P. J. G. M. Dewit, and J. Kuc, Physiol. Plant Pathol.,25, No. 2, 199 (1984).CrossRefGoogle Scholar
  4. 4.
    O. L. Ozeretskovskaya, S. A. Avdyushko, L. I. Chalova, G. I. Chalenko, and L. A. Yurganova, Dokl. Akad. Nauk USSR,22, No. 3, 738 (1987).Google Scholar
  5. 5.
    S. H. Goodnight, W. S. Harris, W. E. Connor, and D. R. Illingworth, Arteriosclerosis,2, No. 2, 87 (1982).CrossRefGoogle Scholar
  6. 6.
    J. Dyerberg, Nutr. Rev.,44, No. 4, 125 (1986).CrossRefGoogle Scholar
  7. 7.
    R. A. Karmali, J. Marsh, and C. Fuchs, J. Natl. Cancer Inst.,73, No. 2, 457 (1984).CrossRefGoogle Scholar
  8. 8.
    K. Punnonen, T. Puustinen, and C. T. Jansen, Prostaglandins,31, No. 2, 263 (1986).CrossRefGoogle Scholar
  9. 9.
    C. Popp-Snijders, J. A. Schouten, A. P. De Jong, and E. A. Van der Veen, Scand. J. Clin. Invest.,44, No. 1, 39 (1984).CrossRefGoogle Scholar
  10. 10.
    M. M. Gottschlich and J. W. Alexander, J. Parent. Enter. Nutr.,11, No. 1, 80 (1987).CrossRefGoogle Scholar
  11. 11.
    S. V. Khotimchenko and V. I. Svetashev, Biol. Morya, No. 6, 3 (1987).Google Scholar
  12. 12.
    E. H. Gruger, R. W. Nelson, and M. E. Stansby, J. Am. Oil Chem. Soc.,41, No. 3, 622 (1961).Google Scholar
  13. 13.
    N. Haagsma, C. M. Van Gent, J. B. Luten, R. W. De Jong, and E. Van Doorn, J. Am. Oil Chem. Soc.,59, No. 32, 117 (1982).CrossRefGoogle Scholar
  14. 14.
    S. Tokiwa, A. Kanazawa, and S. Teshima, Bull. Jpn. Soc. Sci. Fish.,47, No. 5, 675 (1981).CrossRefGoogle Scholar
  15. 15.
    V. E. Vas'kovskii and N. A. Romashina, USSR Inventors' Certificate No. 973128; Byul. Izobret., No. 42, 16 (1982).Google Scholar
  16. 16.
    S. V. Khotimchenko and V. I. Svetashev, Biol. Morya, No. 5, 45 (1983).Google Scholar
  17. 17.
    H. Schlenk, Prog. Chem. Fats Other Lipids,2, 243 (1954).CrossRefGoogle Scholar
  18. 18.
    A. M. Abu-Nasr, W. M. Potts, and R. T. Holman, J. Am. Oil Chem. Soc.,31, No. 1, 16 (1954).CrossRefGoogle Scholar
  19. 19.
    W. W. Christie, Lipid Analysis, Pergamon Press, Oxford (1973), p. 91.Google Scholar
  20. 20.
    N. A. Romashina, Biol. Morya., No. 1, 66 (1983).Google Scholar

Copyright information

© Plenum Publishing Corporation 1991

Authors and Affiliations

  • N. A. Romashina
  • V. E. Vas'kovskii

There are no affiliations available

Personalised recommendations