Chemistry of Natural Compounds

, Volume 25, Issue 1, pp 112–115 | Cite as

Immobilization of snake venom on epoxy-activated Silokhroms

  • O. V. Ostapenko
  • V. V. Chupin
  • G. A. Serebrennikova
  • R. P. Evstigneeva


The production of immobilized phospholipase A2 preparations by the covalent addition of the proteins of viper venom to Silokhroms containing epoxide groups is described. The dependence of the amount of protein bound to the support on its concentration and on the amount of epoxide groups in the sorbent has been investigated. The phospholipase activity of the preparations obtained did not depend on the amount of immobilized enzyme but was determined by diffusional factors.


Organic Chemistry Epoxide Immobilize Enzyme Snake Venom Covalent Addition 
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Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • O. V. Ostapenko
  • V. V. Chupin
  • G. A. Serebrennikova
  • R. P. Evstigneeva

There are no affiliations available

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