Abstract
Marked transient increases in serum alkaline phosphatase activity were found in three siblings with upper respiratory tract infections. This supports observations suggesting an infectious origin of the condition termed “transient hyperphosphatasaemia of infancy and early childhood”.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Abbreviations
- AP:
-
alkaline phosphatase
- ITH:
-
isolated transient hyperphosphatasaemia
References
Frank U, Kruse K (1985) Evidence for infectious origin of isolated transient hyperphosphatasemia. Eur J Pediatr 143:323–324
Kraut JR, Metrick M, Maxwell NR, Kaplan MM (1985) Isoenzyme studies in transient hyperphosphatasemia of infancy. Am J Dis Child 139:736–740
Mahy BWJ, Rowson KEK, Parr CW (1967) Studies on the mechanism of action of Riley virus. IV. The reticuloendothelial system and impaired plasma enzyme clearance in infected mice. J Exp Med 125:277–288
Posen S, Lee C, Vines R, Kilham H, Latham S, Keefe JF (1977) Transient hyperphosphatasemia of infancy — an insufficiently recognized syndrome. Clin Chem 23:292–294
Stein P, Roslki SB, Foo AY, Hjelm M (1987) Transient hyperphophatasemia of infancy and early childhood: clinical and biochemical features of 21 cases and literature review. Clin Chem 33:313–318
Steinherz PG, Steinherz LJ, Nisselbaum JS, Murphy ML (1984) Transient, marked, unexplained elevation of serum alkaline phophatase. J Am Med Assoc 252:3289–3292
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kruse, K., Kurz, N. Further evidence for infectious origin of isolated transient hyperphosphatasaemia. Eur J Pediatr 148, 453–454 (1989). https://doi.org/10.1007/BF00595912
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00595912