European Journal of Pediatrics

, Volume 148, Issue 5, pp 431–434 | Cite as

Unusual course of a chlamydia pneumonia in an infant with IgG2/IgG4-deficiency

  • T. Klingebiel
  • A. Pickert
  • R. Dopfer
  • M. B. Ranke
  • R. Siedner
Infectious Diseases
  • 16 Downloads

Abstract

An unusual case ofChlamydia trachomatis (C. trachomatis) pneumonia, complicated by the development of a pneumothorax, is reported in an IgG2/IgG4 deficient infant delivered by caesarean section.C. trachomatis was isolated initially from a throat smear and subsequently from pleural effusions. Serological examinations using the complement fixation test were negative in sera of both mother and child. However, using immunofluorescence the presence of an acute or recent infection was confirmed by IgM-antibodies in the serum of the infant and IgA-antibodies in the serum of the mother. At the age of 7 months the girl suffered from impetigo contagiosa which was partially resistant to antibiotic treatment. IgG-subclass deficiency was diagnosed after the onset of this disease and the girl was then treated by immunoglobulin transfusion.

Key words

Chlamydia trachomatis Impetigo contagiosa IgG-sub-class-deficiency Pneumothorax 

Abbreviations

C. trachomatis

Chlamydia trachomatis

ELISA

enzyme linked immuno assay

IFT

immunofluorescence technique

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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • T. Klingebiel
    • 1
  • A. Pickert
    • 3
  • R. Dopfer
    • 1
  • M. B. Ranke
    • 2
  • R. Siedner
    • 1
  1. 1.Abteilung für Pädiatrische Hämatologie und Onkologie der Universitäts-KinderklinikTübingenGermany
  2. 2.Abteilung Allgemeine Kinderheilkunde mit Poliklinik der Universitäts-KinderklinikTübingenGermany
  3. 3.Abteilung Innere Medizin IVMedizinische Universitätsklinik mit PoliklinikTübingenGermany

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