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Age changes of cross-links in rat skin elastin

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Summary

The content of elastin was determined in the skin of rats aged 2–33 months; it decreased with age of the skin, and the diameter of elastic fibers increased. In elastin isolated from the rat skin, the content of isodesmosine and desmosine was 3–10 times lower than in that from bovine ligamentum nuchae; both isomers increased with advancing age of the skin.

Zusammenfassung

Es wurde der Elastingehalt in der Haut der 2–33 Monate alten Ratten festgestellt. Der Elastingehalt sank entsprechend dem Alter, und die Dichte der elastischen Fasern erhöhte sich. Im isolierten Elastin sind Isodesmosin und Desmosin 3–10 mal niedriger als in dem vom Rind-Ligamentum nuchae, und steigen entsprechend dem fortschreitenden Alter der Haut.

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Bartoš, F., Ledvina, M. Age changes of cross-links in rat skin elastin. Arch. Derm. Forsch. 241, 134–140 (1971). https://doi.org/10.1007/BF00595366

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