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Xylosyltransferase — a marker enzyme of chondroitin sulphate synthesis in developing liver

Xylosyltransferase — ein Markerenzym der Chondroitinsulfatsynthese in der sich entwickelnden Leber

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Conclusions

A rapidly decreasing CS synthesis in developing rat liver was shown. Parallel to the declining rate of CS biosynthesis the activity of xylosyltransferase is reduced. These findings point to a regulatory role of this enzyme in proteochondroitin sulphate synthesis in rat liver. Whether changes in CS synthesis have to be due to a changed synthetic capacity of hepatocytes or to the decreased number of hemopoietic cells in developing rat liver is not yet definitely clear and needs further investigation.

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Authors and Affiliations

  1. Lehrstuhl für Klinische Chemie und Pathobiochemie der Medizinischen Fakultät der RWTH Aachen, Pauwelsstraße, D-5100, Aachen, Federal Republic of Germany

    Anette Vasel, B. Wolf, A. M. Gressner & H. Greiling

Authors
  1. Anette Vasel
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  2. B. Wolf
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  3. A. M. Gressner
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  4. H. Greiling
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Vasel, A., Wolf, B., Gressner, A.M. et al. Xylosyltransferase — a marker enzyme of chondroitin sulphate synthesis in developing liver. Z. Anal. Chem. 317, 707–708 (1984). https://doi.org/10.1007/BF00593864

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  • DOI: https://doi.org/10.1007/BF00593864

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