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Neuroradiology

, Volume 32, Issue 4, pp 328–330 | Cite as

MRI findings in the mild type of mucopolysaccharidosis II (Hunter's syndrome)

  • S. Shimoda-Matsubayashi
  • Y. Kuru
  • H. Sumie
  • T. Ito
  • N. Hattori
  • Y. Okuma
  • Y. Mizuno
Case Reports

Summary

Neuroradiological findings in a 44-year-old male with the typical mild type of Hunter's disease are reported. Cranial MRI revealed patchy areas of increased and decreased signals in T1- and T2-weighted images in the thalamus and the basal ganglia giving rise to a honey comb-like appearance as a whole. The deep white matter showed high signals in the T2-weighted image. To our knowledge, the honey comb-like appearance has never been reported in this disorder. Deposition of mucopolysaccharides and/or glycolipids and increase in fluid content seem to be responsible for these changes.

Key words

Hunter's syndrome Mucopolysaccharidosis MRI CT 

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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • S. Shimoda-Matsubayashi
    • 1
  • Y. Kuru
    • 2
  • H. Sumie
    • 2
  • T. Ito
    • 1
  • N. Hattori
    • 1
  • Y. Okuma
    • 1
  • Y. Mizuno
    • 1
  1. 1.Department of NeurologyJuntendo University School of MedicineTokyoJapan
  2. 2.Department of RadiologyJuntendo University School of MedicineTokyoJapan

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