Pflügers Archiv

, Volume 338, Issue 2, pp 183–186 | Cite as

pH limits of contractility in isolated turtle heart

  • José S. Serrano
  • Harold F. Hardman
  • Joseph J. Barboriak
Short Communications and Technical Notes

Summary

The isolated turtle heart maintains contractility when perfused at pH's that differ greatly from the physiological. This unusual tolerance might indicate that pH sensitive processes in cardiac contractility occur in cell compartments that do not reflect readily changes in the external pH. Otherwise, the turtle heart might possess intracellular mechanisms compensating for wide fluctuations in pH, specially on the alkaline side.

Key words

Extracellular pH Turtle Heart Cardiac Contractility 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Brody, H.: Amer. J. Physiol.93, 190–196 (1930).Google Scholar
  2. Meester, W. D., Hardman, H. F.: J. Pharmacol. exp. Ther.158, 241–247 (1967).Google Scholar
  3. Mines, G. R.: J. Physiol. (Lond.)46, 188–235 (1913).Google Scholar
  4. Robin, E. D.: Nature (Lond.)195, 249–251 (1962).Google Scholar
  5. Smith, H. W.: J. Biol. Chem.82, 651–661 (1929).Google Scholar
  6. Waddell, W. J., Hardman, H. F.: Amer. J. Physiol.199, 1112–1114 (1960).Google Scholar
  7. Williams, J. K.: Biology data book, p. 261, P. L. Atman and D. S. Dittmer, eds. Washington: F.A.S.E.B. 1964.Google Scholar

Copyright information

© Springer-Verlag 1973

Authors and Affiliations

  • José S. Serrano
    • 1
  • Harold F. Hardman
    • 1
  • Joseph J. Barboriak
    • 1
  1. 1.Department of PharmacologyWisconsin School of MedicineMilwaukeeUSA

Personalised recommendations