Pflügers Archiv

, Volume 326, Issue 3, pp 211–222 | Cite as

The effect of sex steroids on the liver glycogen in intact and adrenalectomized rats

  • Nebojša Avdalović
Article

Summary

It appears that the sex hormones and corticosteroids interact in the final outcome of gluconeogenesis. The female rats pre-treated with estradiol lose their liver glycogen on fasting at a lower rate than the rats pre-treated with testosterone or olive oil. Upon injection of cortisol to fasting rats it was shown that estradiol pre-treatment enables rats to accumulate liver glycogen at a faster rate than the pre-treatment with testosterone propionate. Large doses of estradiol but not of testosterone provoke an increased accumulation of liver glycogen in fasting intact but not in fasting adrenalectomized rats.

Key-Words

Liver Glycogen Testosterone Estradiol and Gluconeogenesis Cortisol and Sex Steroids Interaction 

Schlüsselwörter

Leberglykogen Testosteron Oestradiol und Gluconeogenese Cortisol und Sexsteroiden-Wechselwirkung 

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Copyright information

© Springer-Verlag 1971

Authors and Affiliations

  • Nebojša Avdalović
    • 1
  1. 1.Department of Physiology, Faculty of MedicineUniversity of ZagrebZagrebYugoslavia

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