Summary
Adenosine deaminase (ADA), adenylate kinase (AK1), and acid phosphatase (ACP1) red blood cell enzymes were studied for allelic variation in a French-Canadian population from Quebec City, Canada. Allele frequencies in 887 unrelated individuals were for ACP1, ACP1*A: 0.305; ACP1*B: 0.635 and ACP1*C: 0.060, for ADA, ADA*1: 0.969, ADA*2: 0.031, and for AK1, AK1*1: 0.976, AK1*2: 0.024. The allele frequencies for each enzyme were identical to those previously reported in other Caucasian populations.
References
Chagnon YC, Bouchard C, Allard C (1981) Isoelectric focusing of red cell phosphoglucomutase (E.C.:2.7.5.1) at the PGM1 locus in a French-Canadian population. Hum Genet 59:36–38
Divall BC (1981) Studies on the use of isoelectric focusing as a method of phenotyping erythrocyte acid phosphatase. Forensic Sci Int 18:67–78
Harris H, Hopkinson DA (1976) Handbook of enzyme electrophoresis in human genetics. North-Holland, Amsterdam
Mourant AE, Kopec A, Domaniewska-Sobczak K (1976) The distribution of the human blood groups and other polymorphisms. Oxford University Press, London
Radola BJ (1980) Ultrathin-layer isoelectric focusing in 50–100 μm polyacrylamide gels on silanized glass plates or polyester films. In: Radola BJ (ed) Electrophoresis 79. de Gruyter, New York Berlin, pp 79–94
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Couture, L., Chagnon, M., Allard, C. et al. Adenosine deaminase, adenylate kinase and acid phosphatase polymorphism in a French-Canadian population. Hum Genet 75, 188 (1987). https://doi.org/10.1007/BF00591084
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00591084