Surgical Endoscopy

, Volume 8, Issue 10, pp 1216–1220 | Cite as

Interleukin-6 and coagulation-fibrinolysis fluctuations after laparoscopic and conventional cholecystectomy

  • G. Vander Velpen
  • F. Penninckx
  • R. Kerremans
  • J. Van Damme
  • J. Arnout
Original Articles

Abstract

This study assesses quantitatively the fluctuations of interleukin-6 (IL-6) and coagulationfibrinolysis proteins in patients undergoing elective laparoscopic (n=14) and conventional (n=10) cholecystectomy. The patients in both groups were comparable in age and sex. Serum levels of interleukin-6, and plasma levels of fibrinogen, von Willebrand factor-antigen, tissue-type plasminogen activator-antigen, and plasminogen activator inhibitor-1 were determined for up to 48 h postoperatively. The postoperative changes of all parameters tested were comparable in both patient groups with a trend toward a higher interleukin-6 response at 8 h postincision (NS) and a trend toward a higher fibrinolysis inhibition (NS) after conventional cholecystectomy.

Key words

Cholecystectomy Laparoscopic Conventional Surgical stress response Interleukin-6 Coagulation Fibrinolysis 

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Copyright information

© Springer-Verlag New York Inc. 1994

Authors and Affiliations

  • G. Vander Velpen
    • 1
  • F. Penninckx
    • 1
  • R. Kerremans
    • 1
  • J. Van Damme
    • 2
  • J. Arnout
    • 3
  1. 1.Department of Abdominal Surgery, U.Z. GasthuisbergUniversity of LeuvenLeuvenBelgium
  2. 2.Department of Virology and Rega Institute, U.Z. GasthuisbergUniversity of LeuvenLeuvenBelgium
  3. 3.Department of Pathophysiology, U.Z. GasthuisbergUniversity of LeuvenLeuvenBelgium

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