Pflügers Archiv

, Volume 306, Issue 4, pp 354–356 | Cite as

A new method for the determination of calcium fluxes in the frog heart by means of high precision measurement of45calcium concentrations

  • R. Niedergerke
  • S. Page
Kurzmitteilungen und Methodisches


Small concentration changes (usually <1%) of [45Ca] in radioactive perfusate of frog ventricles are used to determine calcium movements in heart cells. The procedure for high precision analysis of [45Ca] and its application to flux measurements are described.


Calcium Analysis Heart Muscle 


Calciumanalyse Herzmuskel 


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  1. Niedergerke, R.: J. Physiol. (Lond.)167, 515–550 (1963).Google Scholar
  2. —, andM. S. Talbot: Pflügers Arch.306, 357–360 (1969).Google Scholar

Copyright information

© Springer-Verlag 1969

Authors and Affiliations

  • R. Niedergerke
    • 1
  • S. Page
    • 1
  1. 1.Department of BiophysicsUniversity College LondonLondonUK

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