Pflügers Archiv

, Volume 306, Issue 4, pp 320–328 | Cite as

Effects on rats of CSF from sleep-deprived rabbits

  • David A. Ringle
  • Betty L. Herndon


Rabbits were sleep-deprived for 72 hours in revolving drum sleep deprivation cages. Cerebrospinal fluid samples obtained from these sleep-deprived and from control rabbits were infused intraventricularly into rats to assay for the presence of a sleep-promoting material in the sleep-deprived rabbit CSF. Effects on ECoG patterns, ambulatory activity and behavior of the assay rats failed to show sleep-promoting properties for the CSF from sleep-deprived rabbits.


Sleep Sleep Deprivation Cerebrospinal Fluid ECoG Recording Ambulatory Activity 


Schlaf Schlafberaubung Cerebrospinalflüssigkeit Elektrocorticogramm Ambulante Bewegungen 


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Copyright information

© Springer-Verlag 1969

Authors and Affiliations

  • David A. Ringle
    • 1
  • Betty L. Herndon
    • 1
  1. 1.Life Sciences DivisionMidwest Research InstituteKansas CityUSA

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