Advertisement

Pflügers Archiv

, Volume 394, Issue 3, pp 239–242 | Cite as

Dynamic properties of renshaw cells: Equivalence of responses to step changes in recruitment and discharge frequency of motor axons

  • H. -G. Ross
  • S. Cleveland
  • A. Kuschmierz
Excitable Tissues and Central Nervous Physiology

Abstract

In decerebrate cats, the dynamic responses of Renshaw cells to step changes in input were determined seperately both for changes in the number of α-axons excited and for changes in the frequency at which they were stimulated. Together, these two input variables to the Renshaw cells describe the level of activity in the motor output from the spinal cord.

In either case, the dynamic responses of the interneurons depend only on their static activity before and after an input step occurs, but are otherwise indistinguishable. This favors the interpretation that the two input variables are equivalent under dynamic conditions, i.e., Renshaw cells respond to total motor output.

Key words

Motor control Renshaw cells Dynamic properties 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adrian ED, Bronk DW (1928) The discharge of impulses in motor nerve fibres. I. Impulses in single fibres of the phrenic nerve. J Physiol 66:81–101Google Scholar
  2. Adrian ED, Bronk DW (1929) The discharge of impulses in motor nerve fibres. II. The frequency of discharge in reflex and voluntary contractions. J Physiol 67:119–151Google Scholar
  3. Cleveland S, Ross HG (1977) Dynamic properties of Renshaw cells: Frequency response characteristics. Biol Cybern 27:175–184Google Scholar
  4. Cleveland S, Ross HG (1981) Antidromic inhibition of spinal motoneurons reflects the response properties of Renshaw cells. Pflügers Arch 389:R33Google Scholar
  5. Cleveland S, Kuschmierz A, Ross HG (1981) Static input-output relations in the spinal recurrent inhibitory pathway. Biol Cybern 40:223–231Google Scholar
  6. Deliagina TG, Feldman AG (1981) Activity of Renshaw cells during fictive scratch reflex in the cat. Exp Brain Res 42:108–115Google Scholar
  7. Eccles JC, Fatt P, Koketsu K (1954) Cholinergic and inhibitory synapses in a pathway from motor-axon collaterals to motoneurones. J Physiol 126:524–562Google Scholar
  8. Frank K, Fuortes MGF (1956) Unitary activity of spinal interneurons of cats. J Physiol 131:424–435Google Scholar
  9. Granit R, Renkin B (1961) Net depolarization and discharge rate of motoneurones, as measured by recurrent inhibition. J Physiol 158:461–475Google Scholar
  10. Haase J (1963) Die Transformation des Entladungsmusters der Renshaw-Zellen bei tetanischer antidromer Reizung. Pflügers Arch 276:471–480Google Scholar
  11. Haase J, Cleveland S, Ross HG (1975) Problems of postsynaptic autogenous and recurrent inhibition in the mammalian spinal cord. Rev Physiol Biochem Pharmacol 73:73–129Google Scholar
  12. Hultborn H, Pierrot-Deseilligny E (1979) Input-output relations in the pathway of recurrent inhibition to motoneurones in the cat. J Physiol 297:267–287Google Scholar
  13. Hultborn H, Lindström S, Wigström H (1979) On the function of recurrent inhibition in the spinal cord. Exp Brain Res 37:399–403Google Scholar
  14. Kernell D, Sjöholm H (1975) Recruitment and firing rate modulation of motor unit tension in a small muscle of the cat's foot. Brain Res 98:57–72Google Scholar
  15. van Keulen LCM (1979) Relations between individual motoneurons and individual Renshaw cells. Neurosci Lett [Suppl] 3:S313Google Scholar
  16. van Meter WG (1978) Temporal analysis of post tetanic depression of antidromically activated Renshaw cells. Soc Neurosci [Abstr] 4:572Google Scholar
  17. Milner-Brown HS, Stein RB, Yemm R (1973a) The orderly recruitment of human motor units during voluntary isometric contractions. J Physiol 230:359–370Google Scholar
  18. Milner-Brown HS, Stein RB, Yemm R (1973b) Changes in firing rate of human motor units during linearly changing voluntary contractions. J Physiol 230:371–390Google Scholar
  19. Noske W, Ross HG, Cleveland S, Haase J (1974) Decrease of antidromic inhibition due to orthodromic tetanic stimuli. Pflügers Arch 350:223–230Google Scholar
  20. Ostle B (1963) Statistics in research. Iowa University Press, Ames, IowaGoogle Scholar
  21. Pompeiano O, Wand P, Sontag KH (1975) The relative sensitivity of Renshaw cells to orthodromic group Ia volleys caused by static stretch and vibration of extensor muscles. Arch Ital Biol 113:238–279Google Scholar
  22. Renshaw B (1946) Central effects of centripetal impulses in axons of spinal ventral roots. J Neurophysiol 9:191–204Google Scholar
  23. Ross HG, Cleveland S, Haase J (1972) Quantitative relation of Renshaw cell discharge to monosynaptic reflex height. Pflügers Arch 332:73–79Google Scholar
  24. Ross HG, Cleveland S, Wolf E, Haase J (1973) Changes in the excitability of Renshaw cells due to orthodromic tetanic stimuli. Pflügers Arch 344:299–307Google Scholar
  25. Ross HG, Cleveland S, Haase J (1975) Contribution of single motoneurons to Renshaw cell activity. Neurosci Lett 1:105–108Google Scholar
  26. Ross HG, Cleveland S, Haase J (1976) Qualitative relation between discharge frequencies of a Renshaw cell and an intracellularly depolarized motoneuron. Neurosci Lett 3:129–132Google Scholar
  27. Ryall RW, Piercey MF, Polosa C, Goldfarb J (1972) Excitation of Renshaw cells in relation to orthodromic and antidromic excitation of motoneurons. J Neurophysiol 35:137–148Google Scholar
  28. Stein RB (1974) Peripheral control of movement. Physiol Rev 54: 215–243Google Scholar

Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • H. -G. Ross
    • 1
  • S. Cleveland
    • 1
  • A. Kuschmierz
    • 1
  1. 1.Physiologisches Institut II der Universität DüsseldorfDüsseldorfFederal Republic of Germany

Personalised recommendations