Summary
The CT scan's of 22 patients with lissencephaly type I, a severe developmental disorder of the cerebral cortex, were studied. In 6 patients a magnetic resonance (MR), scan was also performed. The CT and MR scans of the lissencephaly patients were compared to a control group consisting of 49 patients with a normal CT or MR scan. In lissencephaly the cortical thickness was always larger than 10 mm, as compared to less than 7 mm in the normal situation. In lissencephaly the WSF/DSF index (with/depth of the sylvian fissure) was always larger than 0.29, while in the normal situation less than 0.25.
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de Rijk-van Andel, J.F., van der Knaap, M.S., Valk, J. et al. Neuroimaging in lissencephaly type I. Neuroradiology 33, 230–233 (1991). https://doi.org/10.1007/BF00588223
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DOI: https://doi.org/10.1007/BF00588223