Abstract
In a group of 69 patients with pituitary tumours, 12 were found to have evidence of intratumoral haemorrhage on MRI, characterized by high signal intensity on short TR/TE sequences. This was verified in all but 1 patient. The majority of the bleedings occurred in macroadenomas. Five (42%) were prolactinomas and 4 (33%) were non-functioning adenomas. There were 2 GH- and 1 ACTH-secreting tumours. All 5 patients with prolactinomas were on bromocriptine medication. Two of the patients had a clinical picture of pituitary apoplexy. The haemorrhage was not large enough to prompt surgery in any of the patients. However, surgical verification of the diagnosis was obtained in 5 cases, while 6 patients were examined with follow-up MRI.
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References
Kucharczyk W, Davis D, Kelly W, Sze G, Norman D, Newton T (1986) Pituitary adenomas: high-resolution MR imaging at 1.5 T. Radiology 161:761–765
Davis P, Hoffman J Jr, Spencer T, Tindall G, Braun I (1987) MR imaging of pituitary adenoma: CT, clinical, and surgical correlation. AJNR 8:107–112
Mark L, Pech P, Daniels D, Charles C, Williams A, Haughton V (1984) The pituitary fossa: a correlative anatomic and MR study. Radiology 153:453–457
Mikhael M, Ciric I (1988) MR imaging of pituitary tumors before and after surgical and/or medical treatment. J Comput Assist Tomogr 12:441–445
Dietemann J (1990) Magnetic resonance imaging of pituitary adenomas. Diag Interv Radiol 2:5–12
Ostrov S, Quencher R, Hoffman J, Davis P, Hasso A, David N (1989) Hemorrhage within pituitary adenomas: how often associated with pituitary apoplexy syndrome? AJR 153:153–160
Gomori J, Grossman R, Goldberg H, Zimmerman R, Bilaniuk L (1985) Intracranial hematomas: imaging by high-field MR. Radiology 157:87–93
Wakai, S, Takanori F, Teramoto A, Sano K (1981) Pituitary apoplexy: its incidence and clinical significance. J Neurosurg 55:187–193
Yousem D, Arrington J, Zinreich S, Kumar A, Bryan R (1989) Pituitary adenomas: possible role of bromocriptine in intratumoral hemorrage. Radiology 170:239–243
Kjos B, Brant-Zawadski M, Kucharczyk W, Kelly W, Norman D, Newton T (1985) Cystic intracranial lesions: magnetic resonance imaging. Radiology 155:363–369
Bradley W, Schmidt P (1985) Effects of methemoglobin formation on the MR appearance of subarachnoid hemorrhage. Radiology 156:99–103
DiChiro G, Brooks R, Girton M, Caporale T, Wright D, Dwyer A, Horne M (1986) Sequential MR studies of intracerebral hematomas in monkeys. AJNR 7:193–199
Steinbrich W, Huk W (1990) Intracranial herorrhage and iron metabolism. In: Huk W, Gademann G, Friedmann G (eds) MRI of central nervous system diseases. Springer, Berlin Heidelberg New York, p. 5.2
Weissbuch S (1986) Explanation and implications of MR signal changes within pituitary adenomas after bromocriptine therapy. AJNR 7:214–216
Pojunas K, Daniels D, Williams A, Haughton V (1986) MR imaging of prolactin secreting microadenomas. AJNR 7:209–213
Grossman R, Gomori J, Goldberg H, Hackney D, Macchi P, Hecht-Leavitt C, Zimmerman R, Bilaniuk L (1986) Magnetic resonance imaging of hemorrhagic conditions. Acta Radiol (Suppl) 369:53–55
Thulborn K, Sorensen A, Kowall N, McKee A, Lai A (1990) The role of ferritin and hemosiderin in the MR appearance of cerebral hemorrhage: a histopathologic biochemical study in rats. AJNR 11:291–297
Pusey E, Kortman K, Flannigan B, Tsuruda J, Bradley W (1987) MR of craniophyryngiomas: tumor delineation and characterization. AJNR 8:439–444
Redmen C, Hall R (1987) Endocrine disorders in pregnancy. In: Weatherall D, Ledingham J, Warell D (eds) Oxford textbook of medicine. Oxford University Press, New York, pp 11.17–11.21
Wiles C, Redmen C (1987) Neurological disorders and pregnancy. In: Wheatherall D, Ledingham J, Warell D (eds) Oxford textbook of medicine. Oxford University Press, New York, pp 11.35–11.40
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Lazaro, C.M., Guo, W.Y., Sami, M. et al. Haemorrhagic pituitary tumours. Neuroradiology 36, 111–114 (1994). https://doi.org/10.1007/BF00588072
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DOI: https://doi.org/10.1007/BF00588072