, Volume 33, Issue 4, pp 364–367 | Cite as

Serial MR imaging in Creutzfeldt-Jakob disease

  • A. Uchino
  • M. Yoshinaga
  • O. Shiokawa
  • H. Hata
  • M. Ohno
Case Reports


Serial magnetic resonance (MR) imagings of two autopsied patients with Creutzfeldt-Jakob disease (CJD) are presented. Both patients showed a dramatic progression of brain atrophy. The initial MR imagings were, however, interpreted as normal except for localized mild cortical atrophy in one patient. When a normal MR image is obtained in a demented middle-aged or aged patient, CJD may still need to be ruled out: follow up MR imaging may be useful.

Key words

Creutzfeldt-Jakob disease Brain atrophy White matter degeneration Magnetic resonance imaging 


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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • A. Uchino
    • 1
  • M. Yoshinaga
    • 2
  • O. Shiokawa
    • 2
  • H. Hata
    • 1
  • M. Ohno
    • 1
  1. 1.Department of RadiologyKyushu Rosai HospitalKitakyushuJapan
  2. 2.Stroke Care UnitKyushu Rosai HospitalKitakyushuJapan

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