Summary
Studies on the interaction of two dopamine (DA) agonists (selected as most specific): apomorphine (APO) and 1, 3-dimethyl-5-aminoadamantane (DMAA) with serotonin (5-HT) and noradrenaline (NA) brain systems have revealed that the drugs induce the activation of 5-HT and NA neurons in an indirect way (via primary DA stimulation). These interactions are relevant for some pharmacological effects of DA agonists.
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Maj, J. Dopamine agonists and interaction with other neurotransmitter systems. Naunyn-Schmiedeberg's Arch. Pharmacol. 297 (Suppl 1), S53–S54 (1977). https://doi.org/10.1007/BF00587777
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DOI: https://doi.org/10.1007/BF00587777