Pflügers Archiv

, Volume 341, Issue 2, pp 97–104 | Cite as

Electrical noise from PVC-membranes

  • J. P. L. M. Michalides
  • R. A. M. Wallaart
  • L. J. DeFelice


Voltage fluctuations were measured across a polyvinylchloride (PVC)-membrane, acting as a constraint between two identical aqueous salt solutions. Membranes with de-resistances between about 2 and 10 megohms. cm2 were studied in solutions of KCl between 0.01 and 0.10 moles per liter.

Positive and negative currents between 10 and 100 nanoamps per square centimeter of membrane were passed. The noise was measured in the frequency range between 1.5 and 150 hertz. The spectral density of the noise power, in excess of that measured at equilibrium, was found to be proportional to the mean power being dissipated in the membrane, and inversely proportional to frequency.

Key words

Frequency Analysis Membrane Noise 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. DeFelice, L. J., Michalides, J. P. L. M.: Electrical noise from synthetic membranes. J. Membrane Biol.9, 261–290 (1972).Google Scholar
  2. Johnson, J. B.: Thermal agitation of electricity in conductors. Physic. Rev.32, 97–109 (1928).Google Scholar
  3. Nyquist, H.: Thermal agitation of electrical charge in conductors. Physic. Rev.32, 110–113 (1928).Google Scholar
  4. Siebenga, E., Meyer, A., Verveen, A. W. A.: Membrane shot-noise in electrically depolarized nodes of Ranvier. Pflügers Arch.341, 87–96 (1973).Google Scholar
  5. Siebenga, E., Verveen, A. A.: The dependence of the 1/f noise intensity of the node of Ranvier on membrane potential. Proc. First Europ. Biophysics Congress, vol.5, pp. 219–223 (1971).Google Scholar
  6. Zwanzig, R.: Time-correlation functions and transport coefficients in statistical mechanics. Ann. Rev. Physic. Chem.16, 67–102 (1965).Google Scholar

Copyright information

© Springer-Verlag 1973

Authors and Affiliations

  • J. P. L. M. Michalides
    • 1
    • 2
  • R. A. M. Wallaart
    • 1
  • L. J. DeFelice
    • 1
    • 3
  1. 1.Department of PhysiologyUniversity of LeidenThe Netherlands
  2. 2.Fysiologisch LaboratoriumLeidenThe Netherlands
  3. 3.Department of AnatomyEmory UniversityAtlantaUSA

Personalised recommendations