Skip to main content
SpringerLink
Log in

Differential strength of action of glycine and GABA in hypoglossus nucleus

  • Short Communications and Technical Notes
  • Published:
Pflügers Archiv Aims and scope Submit manuscript

Summary

Glycine and GABA were applied iontophoretically in the hypoglossus nucleus and their effects on the antidromic field potential compared. Preliminary results indicate that GABA may act relatively stronger than glycine in the dorsal dendritic region of the nucleus whilst glycine is more effective in the center of the nucleus, where the somata of the neurones are located. Furthermore, records could be obtained in which GABA preferentially reduced a “dendritic” component of the antidromic field potential.

There is a possibility that actions of glycine and GABA could be unequally distributed over the cell membrane.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bruggencate, G. ten, Sonnhof, U.: Glycine and GABA actions in hypoglossus nucleus and blocking effects of strychnine and picrotoxin. Experientia (Basel)27, 1109 (1971).

    Google Scholar 

  2. Cook, W. A., Jr., Duncan, C. C., Jr., Cangiano, A.: Dendritic inhibition of spinal motoneurones. Proc. XXV int. Congr. Physiol. Sci., Munich, vol. IX, p. 343 (1971).

    Google Scholar 

  3. Curtis, D. R., Duggan, A. W., Felix, D., Johnston, G. A. R.: GABA bicuculline and central inhibition. Nature (Lond.)226, 1222 (1970).

    Google Scholar 

  4. ————: Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat. Brain Res.32, 69–96 (1971).

    Google Scholar 

  5. —, Felix, D.: GABA and prolonged spinal inhibition. Nature (Lond.)231, 187–188 (1971).

    Google Scholar 

  6. Kellerth, J. O., Szumski, A. J.: Effects of picrotoxin on stretch-activated postsynaptic inhibitions in spinal motoneurones. Acta physiol. scand.66, 146–156 (1966).

    Google Scholar 

  7. Lorente de Nó, R.: Action potential of the motoneurones of the hypoglossus nucleus. J. cell. comp. Physiol.29, 207–287 (1947).

    Google Scholar 

  8. Ramon y Cajal, S.: Histologie du systéme nerveux de l'homme et des vertébrés. Consejo superior de investigaciones cientificas. Instituto Ramon y Cajal, Madrid 1952.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Physiologisches Institut der Universität München, Pettenkoferstr. 12, D-8000, München 2, Germany

    H. Altmann, G. ten Bruggencate & U. Sonnhof

Authors
  1. H. Altmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. ten Bruggencate
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. U. Sonnhof
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported by grant Br 242/7, Deutsche Forschungsgemeinschaft.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Altmann, H., ten Bruggencate, G. & Sonnhof, U. Differential strength of action of glycine and GABA in hypoglossus nucleus. Pflugers Arch. 331, 90–94 (1972). https://doi.org/10.1007/BF00587194

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00587194

Key words

Search

Navigation