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The effect of water deprivation and hypertonic salt injection on the oxygen consumption and plasma NaCl concentration in the albino rat

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Summary

O2-consumption of the whole animal was measured for rats deprived of water and food, or food only, at 27°C (for 3 days), 35°C (for 1 day), and in animals injected with NaCl solution intraperitoneally (3 ml/100 g B. W. of 3% NaCl). O2-consumption calculated per gram body weight, decreased by about 20% compared with the control value in animals deprived of water at 27°C, but increased by about 9% in animals deprived of water at 35° C. A 15% to 40% increase in the O2-consumption over the control value was found in the salt injected animals. Plasma NaCl concentration increased by about 5% and 10% in the animals deprived of water at 27°C and 35°C respectively; an increase of about 10% was found in the salt injected group. Rectal temperature was not affected by the experimental treatments. It is suggested that the reduction of the extracellular fluid volume for a long period might explain the observed reduction in the O2-consumption for the animals deprived of water at 27°C.

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This study was partially supported by the “National Council for Research and Development” of Israel.

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Katz, U., Borut, A. & Sarne, Y. The effect of water deprivation and hypertonic salt injection on the oxygen consumption and plasma NaCl concentration in the albino rat. Pflugers Arch. 339, 69–77 (1973). https://doi.org/10.1007/BF00586983

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