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Der Anteil der Nebennieren an der Entstehung einiger Veränderungen des Blutes während der mechanischen Asphyxie

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Summary

The effect of mechanical asphyxia, caused by the complete obstruction of trachea, on some parameters of the blood coagulability and on the number of corpuscular elements in the blood, was studied in male rabbits. The mechanical asphyxia resulted already after 2.5 to 3.0 min in the significant shortening of the coagulation time, as well as of the prothrombin time, the recalcification time being unchanged. The number of thrombocytes, eosinophils was significantly diminished, the number of leucocytes and lymphocytes was on the contrary greater. The finding of the elevated coagulability of the blood during the acute phase of the mechanical asphyxia suggests, that the finding of the liquid blood in corpses, died for instance owing to strangulation is secondary, caused probably by the activation of the fibrinolysis.

The adrenal hormones play in the origin of the above mentioned changes of the blood an important role, because after the bilateral adrenalectomy the mechanical asphyxia did not influence neither the coagulation time nor the prothrombin time. The number of lymphocytes and eosinophils did not change and the number of leucocytes was even lower. Adrenalectomy did not influence the reaction of thrombocytes on asphyxia.

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Literatur

  1. Adams-Ray, J.: Adreno-sympathic activity and the pathogenesis of thrombosis. Thrombose und Embolie. Basel: Benno Schwabe & Co. 1954.

    Google Scholar 

  2. Ambanelli, U., G. Catbiani, A. G. Dettori eO. Ponari: Studio degli effetti dell adrenalina sulla emocoagulatione a dulla fibrinolisi. Haematologica48, 483 (1963).

    Google Scholar 

  3. Andrejenko, G. V.: Fibrinoliz, chimija i fiziologija processa. Moskau: Medicina 1967.

    Google Scholar 

  4. Barbashova, Z. I., K. Krofta, J. Procházka, K. Rakušan, J. Skrivanová, andO. Poupa: The effect of adrenalectomy on adaptation to hypoxia in the rat. Physiol. bohemoslov.14, 324 (1965).

    Google Scholar 

  5. Cannon, W. B.: Bodily changes in pain, hunger, fear and page, ed. 2. New York: B. Appleton-Century Co. 1929.

    Google Scholar 

  6. Casertano, F., andF. Piccinini: In vivo fibrinolytic effects of histamine. Arch. Pat. Clin. med.15, 2, 267 (1959).

    Google Scholar 

  7. Cession-Fossion, A., etJ. Troquet: Action de l'asphyxie sur la teneue en catécholamines des surrénales du rat. Arch. int. Physiol.72, 661 (1964).

    Google Scholar 

  8. Clarke, R. L., andE. E. Cliffton: Oxygen saturation and spontaneous fibrinolytic activity. Amer. J. med. Sci.244, 466 (1962).

    Google Scholar 

  9. Cliffton, E. E.: Review of clinical experience with clothing agents. Amer. J. Cardiol.6, 476 (1960).

    Google Scholar 

  10. Donner, L.: Akutní defibrinační syndrom. (Das akute Defibrinationssyndrom.) Haematolog. Tagg, Pilsen, 16.–17. 6. 1967.

  11. Fearnley, G. R.: Spontaneous fibrinolysis. Amer. J. Cardiol.6, 371 (1960).

    Google Scholar 

  12. Hirsch, H., U. Beneicke u.D. Popeskovič: Die Entstehung von Thrombocytenaggregaten durch Asphyxia beim Hund. Pflügers Arch. ges. Physiol.281, 201 (1964).

    Google Scholar 

  13. Jegorov, P. J., andV. M. Pančenko: Characteristics of thrombogenic indices and fibrinolytic activity of the blood related to therepeutic use of hormones of the pituitary and adrenal cortex. Ter. Arch.33, 21 (1961).

    Google Scholar 

  14. Kovalčík, V., u. P.Hrdina: Vplyv reserpinu a niektorých adrenolytík na antikoagulačnú účinnost pelentanu. (Der Einfluß des Reserpins und einiger Adrenolytika auf die Antikoagulationswirkung des Pelentans.) Abschliessender Forschungsbericht. Bratislava 1966.

  15. Lee, R. J., u.P. D. White: Zit. nach 16.

    Google Scholar 

  16. Netoušek, M.: Klinická hematologie. (Klinische Hématologie.) Praha: SZdN 1962.

    Google Scholar 

  17. Im Obersteg, J. I.: Tod und Blutgerinnung. Diese Z.43, 177 (1954).

    Google Scholar 

  18. Quick, A. J.: The haemorrhagic diseases and the physiology of haemostasia. Thomas Springfield: 1942.

  19. Rajskina, M. E., iZ. T. Samojlova: Nervnyje vlijania na skorost' svertyvanija krovi pri eksperimentalnom ateroskleroze. Pat. Fiziol. éksp. Ter.5(I), 40 (1961).

    Google Scholar 

  20. Selye, H.: The general adaptation syndrom and dieseases of adaptation. J. clin. Endocr.6, 117 (1964).

    Google Scholar 

  21. Serrano, P. A., J. R. Monroy, A. Ramiréz del Angel, B. Chavéz Lara, andA. Lerdo de Tejada: Changes of tissues serotonin and catecholamine concentrations after asphyxia and anoxia. Dis. Chest.49, 507 (1966).

    Google Scholar 

  22. Sherky, S., R. J. Lindemayer, A. P. Fletcher, andN. Alkjaersig: Studies on enhanced fibrinolytic activity in man. J. clin. Invest.38, 810 (1959).

    Google Scholar 

  23. Singh, J., andJ. T. Oester: The possible effect of nicotine on the human blood clotting time in vitro. Arch. int. Pharmacodyn.148, 237 (1964).

    Google Scholar 

  24. Stern, L., J. Leduc, andJ. Lind: Hypoxia as a stimals to catecholamine excretion in the newborn infant. Acta paediat.53, 13 (1964).

    Google Scholar 

  25. Suzuki, T., K. Yamashita, K. Hirai, K.-I. Kurouji, andH. Yoshio: Adrenal 17-hydroxycorticosteroid secretion in response to cyanide anoxia. Pflügers Arch. ges. Physiol.185, 2, 119 (1965).

    Google Scholar 

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Kokavec, M., Barta, E., Krsek, H. et al. Der Anteil der Nebennieren an der Entstehung einiger Veränderungen des Blutes während der mechanischen Asphyxie. Dtsch. Z. ges. gerichtl. Med. 64, 49–55 (1968). https://doi.org/10.1007/BF00586805

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  • DOI: https://doi.org/10.1007/BF00586805

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