Summary
The discharge of afferent impulses recorded from the vagus nerve in isolated frog's lung preparations showed a marked increase both during and after deflation of the lung. A quantitative analysis of the afferent discharge in slowed and sudden deflation experiments demonstrated that it cannot be related to deflation velocity of the lung and that it appears to be depending both on the air volume previously inflated and on the duration of previous inflation. The deflation discharge is interpreted as due to receptors responding to mechanical forces arising from the rearrangement taking place in the pulmonary structures during and after deflation and seem therefore to be anchored to “non-elastic” substructures present in the pulmonary network.
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This study was supported by grants from the Consiglio Nazionale delle Ricerche (Impresa Elettrofisiologia), Roma (Italy).
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Taglietti, V., Casella, C. Deflation receptors in frog's lung. Pflugers Arch. 304, 81–89 (1968). https://doi.org/10.1007/BF00586721
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DOI: https://doi.org/10.1007/BF00586721