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Pflügers Archiv

, Volume 345, Issue 4, pp 317–326 | Cite as

Transport of amino-acids and sugars by the dog colonic mucosa

  • J. W. L. Robinson
  • A. -L. Luisier
  • V. Mirkovitch
Article

Summary

Dog colon mucosa is able to concentrate amino-acids and sugars against a concentration gradient during incubation in vitro. Amongst other species tested, this property is only shared, to any reasonable extent, by the mouse colon.

The properties of the dog colon transport systems have much in common with corresponding mechanisms in the small intestine (Na+-dependence, energy-dependeace, saturation kinetics), but their capacities are considerably lower.

The difference between species (rats, guinea-pigs, mice and humans) is probably quantitative rather than qualitative in nature, since entry into rat colon slices is affected by the absence of Na+ ions and inhibited by homologues.

Key words

Colonic Transport Dog Colon Amino-acid Transport Sugar Transport 

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Copyright information

© Springer-Verlag 1973

Authors and Affiliations

  • J. W. L. Robinson
    • 1
  • A. -L. Luisier
    • 1
  • V. Mirkovitch
    • 1
  1. 1.Départment de Chirurgie ExpérimentaleHôpital Cantonal UniversitaireLausanneSuisse

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