Summary
Dog colon mucosa is able to concentrate amino-acids and sugars against a concentration gradient during incubation in vitro. Amongst other species tested, this property is only shared, to any reasonable extent, by the mouse colon.
The properties of the dog colon transport systems have much in common with corresponding mechanisms in the small intestine (Na+-dependence, energy-dependeace, saturation kinetics), but their capacities are considerably lower.
The difference between species (rats, guinea-pigs, mice and humans) is probably quantitative rather than qualitative in nature, since entry into rat colon slices is affected by the absence of Na+ ions and inhibited by homologues.
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Robinson, J.W.L., Luisier, A.L. & Mirkovitch, V. Transport of amino-acids and sugars by the dog colonic mucosa. Pflugers Arch. 345, 317–326 (1973). https://doi.org/10.1007/BF00585850
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DOI: https://doi.org/10.1007/BF00585850