Summary
The changes in contraction time (CT) and histochemical muscle fibre pattern are compared with respect to ATPase activity of the slow soleus muscle of the guinea-pig during regeneration in free grafts and reinnervation after nerve interruption. Interruption of the nerve by crushing at birth results first in prolongation of CT which later returns to normal (control) values. A homogeneous fibre pattern is established related to the homogeneity of the motor units constituting the muscle. In the regenerating muscle CT and muscle fibre pattern of the graft repeat the changes during postnatal development, i.e. CT shows progressive prolongation accompanied by transformation of a heterogeneous (fibres of high and low ATPase activity) to a homogeneous (fibres of low activity only) fibre pattern. However, the regenerating muscle also shows an initial phase with slow CT. Thus the changes in reinnervation and regeneration of the muscle after birth differ, the reinnervated muscle revealing only prolongation, the regenerated muscle a temporary shortening followed by prolongation, i.e. a biphasic development of CT.
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Ashmore, C. R., Robinson, D. W., Rattray, P., Doerr, L.: Biphasic development of muscle fibres in the fetal lamb. Exp. Neurol.37, 241–255 (1972)
Askanas, V., Shafiq, S. A., Milhorat, A. T.: Histochemistry of cultured aneural chick muscle. Morphological maturation without differentiation of fiber types. Exp. Neurol.37, 218–230 (1972)
Buller, A. J. Buller, J. C., Eccles, R. M.: Differentiation of fast and slow muscles in the cat hind limb. J. Physiol. (Lond.)150, 399–416 (1960)
Buller, A. J., Eccles, J. C., Eccles, R. M.: Interactions between motoneurones and muscles in respect to the characteristic speeds of their responses. J. Physiol. (Lond.)150, 417–439 (1960)
Carlson, B. M., Gutmann, E.: Development of contractile properties of minced muscle regenerates in the rat. Exp. Neurol.36, 239–249 (1972)
Carlson, B., Gutmann, E.: Regeneration of grafts of normal and denervated rat muscles. Contractile properties. Pflügers Arch.353, 215–225 (1975)
Close, R.: Dynamic properties of fast and slow skeletal muscles of the rat during development. J. Physiol. (Lond.)173, 74–95 (1964)
Close, R. I.: Dynamic properties of mammalian skeletal muscle. Physiol. Rev.52, 129–197 (1972)
Fischman, D. A.: Development of striated muscle. In: The structure and function of muscle, vol. I/1 (G. H. Bourne, es.), pp. 75–148 London: Academic Press 1973
Guth, L., Samaha, G. J.: Procedure for the histochemical demonstration of actomyosin ATPase. Exp. Neurol.28, 365–367 (1970)
Gutmann, E., Melichna, J., Syrový, I.: Developmental changes in contraction time, myosin properties and fibre pattern of fast and slow skeletal muscles. Physiol. bohemoslov.23, 19–27 (1974)
Hanzliková, V., Schiaffino, S.: Studies of the effect of denervation in developing muscle. III. Diversification of myofibrillar structure and origin of myofibrillar structure and origin of the heterogeneity of muscle fibre types. Z. Zellforsch.147, 75–85 (1973)
Hník, P., Jirmanová, I., Vyklický, L., Zelená, J.: Fast and slow muscles of the chick after nerve cross-union. J. Physiol. (Lond.)193 309–325 (1967)
Karpati, G., Engel, W. K.: Neuronal trophic function. Arch. Neurol.17, 542–545 (1967)
Kelly, A. M., Schotland, D. L.: The evaluation of the “checkerboard” in rat muscle. In: Research in muscle development and the muscle spindle. Excerpta Medica Int. Congress Series, No. 240, pp. 32–48 (1972)
Padykula, H. A., Hermann E.: The specificity of the histochemical method for adenosine triphosphate. J. Histochem. Cytochem.3, 170–195 (1955)
Riley, D. A.: Histochemical changes in ATPase activity during regeneration of adult skeletal muscle fibres. Exp. Neurol.44, 690–704 (1973)
Rohlíček, V.: An automatic analyzer of muscle contraction. Tech. Dig.61, 383–387 (1968)
Studitsky, A. N.: Experimental surgery of muscles (in Russian). Moscow: Akad. Nauk SSSR 1959
Zelená, J., Jirmanová, I.: Ultrastructure of chicken slow muscle after nerve cross union. Exp. Neurol.38, 272–285 (1973)
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Gutmann, E., Melichna, J.A., Herbrychová, A. et al. Different changes in contractile and histochemical properties of reinnervated and regenerated slow soleus muscles of the guinea-pig. Pflugers Arch. 364, 191–194 (1976). https://doi.org/10.1007/BF00585189
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DOI: https://doi.org/10.1007/BF00585189