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Pflügers Archiv

, Volume 405, Issue 2, pp 141–147 | Cite as

Influence of direct low frequency stimulation on contractile properties of denervated fast-twitch rabbit muscle

  • Wilfred A. Nix
  • Heinz Reichmann
  • Michael J. Schröder
Excitable Tissues and Central Nervous Physiology

Abstract

A continuous electrical 8 Hz impulse pattern imposed directly via implanted electrodes on denervated fast twitch muscle induced changes in its contractile characteristics. Compared with non-stimulated denervated muscle, stimulated muscle showed slowing of contraction time and improved fatigue resistance. The reaction for succinic dehydrogenase was more intense in the denervated stimulated muscle, indicating an increased capacity of oxidative enzymes. The rate of atrophy was not influenced by stimulation. The 8 Hz frequency pattern is the mediator for these changes in the characteristics of denervated muscles. It demonstrates a comparable effect on innervated muscle. The contralateral normal innervated muscle was also influenced by the electrical stimulation. Contraction time as well as twitch tension were increased. This finding is important when using the normal muscle as intraindividual control.

Key words

Denervated muscle Contralateral muscle Electrical stimulation Contractile parameters 

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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • Wilfred A. Nix
    • 1
  • Heinz Reichmann
    • 2
  • Michael J. Schröder
    • 3
  1. 1.Neurologische KlinikUniversitätsklinikenMainzFederal Republic of Germany
  2. 2.Fakultät für BiologieUniversität KonstanzKonitanzFederal Republic of Germany
  3. 3.Abteilung NeuropathologieMedizinische FakultätAachenFederal Republic of Germany

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