The slow inward calcium current is responsible for a part of the contraction of patch-clamped rat myoballs
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The slow inward calcium current and the contractile response were simultaneously recorded in voltage clamped (whole cell patch clamp recording) rat myoballs in primary culture.
The shape of the contraction(T)/potential(V) relationship and the application of the inorganic calcium channel blocker cadmium (1.5 mM), which suppresses a part of the contractile activity, demonstrate the existence of two components of contraction. One of them is related to the slow calcium current.
Key wordsRat skeletal muscle cell culture patch clamp calcium currents contraction
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