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Coexistence ofpolA andrecB mutations ofEscherichia coli in the presence ofsbc, a mutation which indirectly suppressesrecB

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Summary

The double mutantpolA recB ofEscherichia coli K12 which is normally inviable can be “rescued” by a third mutationsbc which results in the appearance of an ATP-independent deoxyribonuclease. Viability ofpolA strains apparently requires either the ATP-dependent deoxyribonuclease which is missing inrecB mutants or the ATP-independent deoxyribonuclease which is present inrecB sbc mutants.

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Authors and Affiliations

  1. Department of Biochemistry, The University, NE1 7RU, Newcastle upon Tyne

    Peter Strike & Peter T. Emmerson

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  1. Peter Strike
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  2. Peter T. Emmerson
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Communicated by R. Pritchard

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Strike, P., Emmerson, P.T. Coexistence ofpolA andrecB mutations ofEscherichia coli in the presence ofsbc, a mutation which indirectly suppressesrecB . Molec. gen. Genet. 116, 177–180 (1972). https://doi.org/10.1007/BF00582226

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  • DOI: https://doi.org/10.1007/BF00582226

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