Pflügers Archiv

, Volume 397, Issue 2, pp 160–163 | Cite as

Technique for producing heart block in closed-chest dogs without electrical recording

  • Bruce R. Ito
  • Eric O. Feigl
Heart, Circulation, Reapiration and Blood; Environmental and Exercise Physiology Instruments and Techniques


An instrument and technique have been devised for the production of complete atrioventricular heart block in anesthetized, closed-chest animals. The instrument is inserted into the right atrium via the right external jugular vein. Localization of the atrioventricular node region by the visualization of intracardiac landmarks with fluoroscopy makes electrical recording unnecessary. Discrete injections of a radiopaque necrosing solution produces the heart block. Procedure time is under 30 min with a success rate of 90%.

Key words

Heart block Atrioventricular conduction Electrocardiogram Cardiac cannula 


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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • Bruce R. Ito
    • 1
  • Eric O. Feigl
    • 1
  1. 1.Department of Physiology and Biophysics SJ-40University of Washington School of MedicineSeattleUSA

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