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Ontogeny and tissue distribution of alcohol dehydrogenase inDrosophila melanogaster

  • Heinrich Ursprung
  • William H. Sofer
  • Natalie Burroughs
Article

Summary

Alcohol dehydrogenase (ADH) activity inDrosophila larvae and adults is localized primarily in fat body, intestine, and Malpighian tubules. In adult males, it occurs furthermore in derivatives of the genital disk.

When expressed as ADH activity/whole organism, increasing values are found throughout the larval stages. Around the time of puparium formation, the activity decreases, to increase again around hatching of the adult.

As the genital disk undergoes metamorphosis, it synthesizes (or activates) ADH rather than acquiring the enzyme from elsewhere in the organism.

Keywords

Alcohol Developmental Biology Adult Male Larval Stage Tissue Distribution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Alkohol-Dehydrogenase(ADH)-Aktivität kommt inDrasophila-Larven und Imagines hauptsächlich im Fettkörper, Verdauungstrakt und Malpighischen Gefäßen vor. In männlichen Imagines findet man das Enzym zudem in Derivaten der Genital-Imaginalscheiben.

Ausgedrückt alsADH- Aktivität/Organismus, steigen dieADH-Werte während der Larvenstadien stetig an. Um die Zeit der Pupariumbildung nehmen sie dann ab und um die Schlüpfzeit zur Imago wieder zu.

Während der Metamorphose synthetisiert (oder aktiviert) die männliche Genitalscheibe ADH; das Enzym wird nicht aus der Umgebung angereichert.

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Copyright information

© Springer-Verlag 1970

Authors and Affiliations

  • Heinrich Ursprung
    • 1
    • 2
  • William H. Sofer
    • 1
  • Natalie Burroughs
    • 1
  1. 1.Department of BiologyThe Johns Hopkins UniversityBaltimore
  2. 2.Laboratory for Developmental BiologyETHZürichSwitzerland

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