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Ion transport across the exocrine glands of the frog skin

  • Analysis of Transepithelial Pathways
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Abstract

Exposure of the intact frog skin to β-adrenergic agonists stimulates chloride secretion by the exocrine glands. The secretory response is dependent on Na in the serosal bath and is inhibited by exposure to ouabain and furosemide. Thus the transport mechanism has properties similar to those described for other exocrine glands. Analysis of3H-ouabain binding sites and determination of intracellular ions by energy dispersive x-ray microanalysis indicates that the transepithelial pathway for Cl flux may be via a distinct group of cells located at the ductal pole of the acinus of two of the gland types; termed mucous and seromucous.

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Authors and Affiliations

  1. Department of Anatomy, Dartmouth Medical School, 03756, Hanover, NH, USA

    John W. Mills

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Mills, J.W. Ion transport across the exocrine glands of the frog skin. Pflugers Arch. 405 (Suppl 1), S44–S49 (1985). https://doi.org/10.1007/BF00581779

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