Archiv für Toxikologie

, Volume 20, Issue 1, pp 1–11 | Cite as

F.D.A. Requirements for food additives in the U.S.A.

  • William B. Deichmann


The methods required to demonstrate that a particular food additive is safe for human consumption depend on the compound involved and on the specific use of the material. In other words, each additive presents a specific and a different problem. Therefore, the toxicological investigation required may range anywhere from a few simple tests to a most comprehensive and time consuming investigation. A most important factor in each of these studies is the investigator himself. There is no simple formula, and certainly no substitute for the mature and considered judgement of the man who by experience and training is qualified to interpret the experimental data.


Experimental Data Cancer Research Food Additive Human Consumption Simple Formula 
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  1. 1.
    Lehman, A. J., W. I. Patterson, B. Davidow, E. C. Hagen, G. Woodard, E. P. Laug, J. P. Frawley, O. G. Fitzhugh, A. R. Bourke, J. H. Draize, A. A. Nelson andB. J. Vos: Procedures for the appraisal of the toxicity of chemicals in foods, drugs and cosmetics. Food. Drug cosmetic. Law J., Vol. 17, No. 10, 579–720 (1962).Google Scholar

Copyright information

© Springer-Verlag 1963

Authors and Affiliations

  • William B. Deichmann
    • 1
  1. 1.Department of PharmacologyUniversity of Miami School of MedicineCoral Gables

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