Chemistry of Natural Compounds

, Volume 18, Issue 1, pp 25–28 | Cite as

Alkylation of methyl 4,6-O-benzylidene-α-D-galactopyranoside

  • V. I. Grishkovets
  • V. Ya. Chirva


The partial alkylation of methyl 4,6-O-benzylidene-α-D-galactopyranoside in dimethylformamide and dimethyl sulfoxide in the presence of barium oxide and hydroxide is described. It has been shown that methylation and benzylation lead predominantly to the 3-alkyl derivatives with yields of 30–40%, benzylation taking place more selectively than methylation. The compounds synthesized have been characterized by their melting points and specific rotations.


Methyl Iodide DMFA Sodium Hydride Monomethyl Ether Benzyl Bromide 


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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • V. I. Grishkovets
  • V. Ya. Chirva

There are no affiliations available

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