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Stimulation of phospholipid turnover by angiotensin II and phenylephrine in proximal convoluted tubules microdissected from mouse nephron

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Abstract

Angiotensin II and phenylephrine significantly increased phospholipid turnover in cortical tubule suspensions. To further localize this effect we studied the32P incorporation into phosphatidylcholine (PC) and phosphatidylinositol (PI) in single dissected proximal convoluted tubules of mouse nephron. Both hormones significantly stimulated32P labeling of PC and PI indicating that the proximal tubule is a target site of angiotensin II and phenylephrine action.

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Authors and Affiliations

  1. Institut für Klinische Chemie, Stadtisches Krankenhaus München-Bogenhausen, Englschalkinger Str. 77, D-8000, München 81, Federal Republic of Germany

    Gabriele Wirthensohn & Walter G. Guder

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  1. Gabriele Wirthensohn
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  2. Walter G. Guder
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Wirthensohn, G., Guder, W.G. Stimulation of phospholipid turnover by angiotensin II and phenylephrine in proximal convoluted tubules microdissected from mouse nephron. Pflugers Arch. 404, 94–96 (1985). https://doi.org/10.1007/BF00581500

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  • DOI: https://doi.org/10.1007/BF00581500

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