Skip to main content
Log in

Is force production in the hypoxic myocardium dependent on cytosolic inorganic phosphate?

  • Heart, Circulation, Respiration and Blood; Environmental and Exercise physiology
  • Short Communication
  • Published:
Pflügers Archiv Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abbreviations

Pi:

Inorganic phosphorus

f:

heart rate

Psyst :

peak isovolumic systolic pressure

References

  1. ALLEN, D. G.; ORCHARD, CH. H. Intracellular calcium concentration during hypoxia and metabolic inhibition in mammalian ventricular muscle. J. Physiol. (Lond) 339, 107–122 (1983)

    Google Scholar 

  2. GODT, R. E.; NOSEK, T. M. The changes in intracellular milieu accompanying fatigue or hypoxia depress the contractile machinery of skeletal and cardiac musle. (Abstract) J. Physiol. 731, 174 p (1986)

    Google Scholar 

  3. KAMMERMEIER, H.; SCHMIDT, P.; JÜNGLING, E. Free energy change of ATP-hydrolysis: a causal factor of early hypoxic failure of myocardium? J. Mol. Cell. Cardiol. 14, 267–277 (1982)

    Google Scholar 

  4. KAWAI, M.; GÜTH, K.; WINNIKES, K.; HAIST, C.; RÜGG, J. C. The effect of inorganic phosphate on the ATP hydrolysis rate and tension transients in chemically skinned rabbit psoas fibres. Pflügers Arch. 408, 1–9 (1987)

    Google Scholar 

  5. KENTISH J. C., ALLEN, D. G.: Is force production in the myocardium directly dependent upon the free energy change of ATP hydrolysis? J. Mol. Cell. Cardiol. 18, 879–882 (1986)

    Google Scholar 

  6. KUSUOKA H.; WEISFELDT M. L. JACOBUS W. E.; MARBAN E. Mechanism of early contractile failure during hypoxia in intact ferret heart: Evidence for modulation of maximal Ca2+-activated force by inorganic phosphate. Circ Res. 59, 270–282 (1986)

    Google Scholar 

  7. LILLE, CH.; KOBINGER, W. Investigations into the bradycardic effects of UL-FS 49 (1, 3, 4, 5-tetrahydro-7, 8-dimethoxy-3-[3-[[2-(3. 4-dimethoxyphenyl) ethyll methyliminol propyl]-2H-3-benzazepin-2-on-hydrochloride) in isolated quinea pig atria. J. Cardiovasc. Pharmacol. 8, 791–797 (1986)

    Google Scholar 

  8. PAUL, R. J.; GLÜCK, E., RÜEGG, J. C. Cross bridge ATP utilization in arterial smooth muscle. Pflügers Arch. 361, 297–299 (1976)

    Google Scholar 

  9. ROEB, E.; KAMMERMEIER H. Automatic adjustment of myocardial contractility to the available energy level: an “energostatic effect”? (Abstract). Pflügers Arch. 408, Suppl. 1, R14 (1987)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kammermeier, H., Roeb, E. Is force production in the hypoxic myocardium dependent on cytosolic inorganic phosphate?. Pflugers Arch. 410, 671–673 (1987). https://doi.org/10.1007/BF00581330

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00581330

Keywords

Navigation